The chemistry and biology of guanidine natural products

RGS Berlinck, S Romminger - Natural Product Reports, 2016 - pubs.rsc.org
Covering: 2012 to 2014. Previous review: Nat. Prod. Rep., 2012, 29, 1382 The present
review discusses the isolation, structure determination, synthesis, biosynthesis and …

Utilization of isatoic anhydride in the syntheses of various types of quinazoline and quinazolinone derivatives

SY Abbas, KAM El-Bayouki… - Synthetic …, 2016 - Taylor & Francis
Isatoic anhydride has attracted a great deal of attention in recent decades. A review of the
methods of preparation of all known quinazoline and quinazolinone derivatives is given …

Guanidines from 'toxic substances' to compounds with multiple biological applications–Detailed outlook on synthetic procedures employed for the synthesis of …

S Tahir, A Badshah, RA Hussain - Bioorganic Chemistry, 2015 - Elsevier
Guanidines to begin with, were thought of being harmful substances associated with
medical ailment. With the advent of World War I and the impact it left on the populations at …

Guanidine dicycloamine-based analogs: green chemistry synthesis, biological investigation, and molecular docking studies as promising antibacterial and …

MAEAAA El-Remaily, MO Aboelez, HAA Ezelarab… - Molecular Diversity, 2024 - Springer
Dicyandiamide (DCD) reacted with amino acids 1a–f to produce biguanides 2 and 4 and
guanidine pyrazolones 3, 5, 6, 7, and 8, according to the reaction. DCD exhibited the …

Palladium-Catalyzed Ortho-Selective C–H Oxidative Carbonylation of N-Substituted Anilines with CO and Primary Amines for the Synthesis of o-Aminobenzamides

X Zhang, S Dong, X Niu, Z Li, X Fan, G Zhang - Organic letters, 2016 - ACS Publications
An efficient, one-pot strategy with high selectivity and high atom economy for the synthesis of
o-aminobenzamides has been developed via palladium-catalyzed ortho-selective C–H …

Metal-free methods for the generation of benzimidazoles and 2-aminobenzimidazoles

PJ Wanjari, N Saha, G Dubey, PV Bharatam - Tetrahedron, 2023 - Elsevier
Benzimidazoles, the important scaffold of various biologically important molecules, can be
synthesized using metal catalyzed and metal-free methodologies. Recently, metal-free …

Nickel‐Catalyzed Decarboxylative Cyclization of Isatoic Anhydrides with Carbodiimides: Synthesis of 2,3‐Dihydroquinazolin‐4(1H)‐ones

Z Zhang, Z Qin, W Chang, J Li, R Fan… - Advanced Synthesis …, 2020 - Wiley Online Library
In this study, a nickel‐catalyzed decarboxylative cyclization of isatoic anhydrides with
carbodiimides was developed. This protocol realized the direct introduction of carbodiimides …

Isatoic anhydride: a fascinating and basic molecule for the synthesis of substituted quinazolinones and benzo di/triazepines

Z Tashrifi… - Current Organic …, 2019 - ingentaconnect.com
This review article is focused on the synthesis of compounds with quinazolinones and benzo
di/triazepine scaffolds. These invaluable derivatives are of great interest in medicinal and …

Seven-membered rings

JH Ryan, C Hyland, J Just, AG Meyer, JA Smith… - Progress in Heterocyclic …, 2013 - Elsevier
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Room-temperature ionic liquid–DMSO promoted and improved one-pot synthesis of 5, 6-diaryl-1, 2, 4-triazines

RS Tamboli, R Giridhar, HM Mande… - Synthetic …, 2014 - Taylor & Francis
An improved and rapid one-pot synthesis of 5, 6-diarylsubstituted-1, 2, 4-triazines in a
mixture of room-temperature ionic liquid 1, 3-dibutylimidazolium bromide [Bbim]+ Br− and …