Double-stranded RNA-mediated interference (RNAi) is a simple and rapid method of
silencing gene expression in a range of organisms. The silencing of a gene is a …

Short interfering RNAs can be used to silence gene expression in a sequence-specific
manner in a process that is known as RNA interference. The application of RNA interference …

In a diverse group of organisms that includes Caenorhabditis elegans, Drosophila, planaria,
hydra, trypanosomes, fungi and plants, the introduction of double-stranded RNAs inhibits …

Double-stranded RNA (dsRNA) directs the sequence-specific degradation of mRNA through
a process known as RNA interference (RNAi). Using a recently developed Drosophila in …

Double-stranded RNA (dsRNA) directs gene-specific, post-transcriptional silencing in many
organisms, including vertebrates, and has provided a new tool for studying gene function …

Posttranscriptional gene silencing (PTGS) in plants results from the degradation of mRNAs
and shows phenomenological similarities with quelling in fungi and RNAi in animals. Here …

The remarkable gene knockdown technique of RNAi has opened exciting new avenues for
genetic screens in model organisms and human cells. Here we describe the current state of …

There is growing interest in the use of cnidarians (corals, sea anemones, jellyfish and
hydroids) to investigate the evolution of key aspects of animal development, such as the …

Both physiological and genetic evidence indicate interconnections among plant responses
to different hormones. We describe a pleiotropic recessive Arabidopsis transposon insertion …

It has long been thought that sequence-specific PTGS required a nucleic acid polymer to
guide mRNA cleavage.[35] The presence of an antisense RNA species complementary to …