Update in the epidemiology, risk factors, screening, and treatment of diabetic retinopathy

KY Lin, WH Hsih, YB Lin, CY Wen… - Journal of diabetes …, 2021 - Wiley Online Library
Diabetic retinopathy (DR) is a common microvascular complication of diabetes mellitus and
is the leading cause of visual loss in the elderly. Hyperglycemia and altered metabolic …

Imaging and biomarkers in diabetic macular edema and diabetic retinopathy

CC Kwan, AA Fawzi - Current diabetes reports, 2019 - Springer
Abstract Purpose of Review Diabetic retinopathy (DR) is the leading cause of acquired
vision loss in adults across the globe. Early identification and treatment of patients with DR is …

MicroRNA-15b targets VEGF and inhibits angiogenesis in proliferative diabetic retinopathy

Y Yang, Y Liu, Y Li, Z Chen, Y Xiong… - The Journal of …, 2020 - academic.oup.com
Background Vascular endothelial growth factor (VEGF)-induced angiogenesis is a critical
compensatory response to microvascular rarefaction in the diabetic retina that contributes to …

MicroRNA biomarkers and platelet reactivity: the clot thickens

N Sunderland, P Skroblin, T Barwari… - Circulation …, 2017 - Am Heart Assoc
Over the last few years, several groups have evaluated the potential of microRNAs
(miRNAs) as biomarkers for cardiometabolic disease. In this review, we discuss the …

Emerging roles for microRNAs in diabetic microvascular disease: novel targets for therapy

Y Zhang, X Sun, B Icli, MW Feinberg - Endocrinology Reviews, 2017 - academic.oup.com
Chronic, low-grade systemic inflammation and impaired microvascular function are critical
hallmarks in the development of insulin resistance. Accordingly, insulin resistance is a major …

The influence of different types of diabetes on vascular complications

J Wei, J Tian, C Tang, X Fang, R Miao… - Journal of diabetes …, 2022 - Wiley Online Library
The final outcome of diabetes is chronic complications, of which vascular complications are
the most serious, which is the main cause of death for diabetic patients and the direct cause …

Retinal and circulating mi RNA expression patterns in diabetic retinopathy: An in silico and in vivo approach

CBM Platania, R Maisto, MC Trotta… - British journal of …, 2019 - Wiley Online Library
Background and Purpose Diabetic retinopathy, a secondary complication of diabetes
mellitus, can lead to irreversible vision loss. Currently, no treatment is approved for early …

MicroRNAs as biomarkers of diabetic retinopathy and disease progression

B Martinez, PV Peplow - Neural regeneration research, 2019 - journals.lww.com
Diabetes mellitus, together with its complications, has been increasing in prevalence
worldwide. Its complications include cardiovascular disease (eg, myocardial infarction …

Urinary miRNA-27b-3p and miRNA-1228-3p correlate with the progression of kidney fibrosis in diabetic nephropathy

F Conserva, M Barozzino, F Pesce, C Divella… - Scientific reports, 2019 - nature.com
Diabetic Nephropathy (DN) is a chronic complication of diabetes and the primary cause of
end stage renal disease. Differential diagnosis for DN requires invasive histological …

Diagnostic and prognostic role of serum miR‐20b, miR‐17‐3p, HOTAIR, and MALAT1 in diabetic retinopathy

OG Shaker, OO Abdelaleem, RH Mahmoud… - IUBMB …, 2019 - Wiley Online Library
Noncoding RNAs are emerging biomarkers for many diseases including diabetic retinopathy
(DR). This study aimed to measure the expression levels of serum miR‐20b, miR‐17‐3p …