Hepatic stellate cells (HSCs) are a significant component of the hepatocellular carcinoma
(HCC) tumor microenvironment (TME). Activated HSCs transform into myofibroblast-like …

As a member of the vertebrate-specific secreted ribonucleases, angiogenin (ANG) was first
isolated and identified solely by its ability to induce new blood vessel formation, and now, it …

The discovery of microRNA (miRNA) sorting into extracellular vesicles (EVs) revealed a
novel mode of intercellular communication and uncovered a link between cellular …

Mitochondrial DNA (mtDNA) released through protein oligomers, such as voltage-
dependent anion channel 1 (VDAC1), triggers innate immune activation and thus …

Background and Aims GAS6 signaling, through the TAM receptor tyrosine kinases AXL and
MERTK, participates in chronic liver pathologies. Here, we addressed GAS6/TAM …

Background and Purpose—Endothelial progenitor cells (EPCs) have been extensively
investigated as a therapeutic approach for repairing the vascular system in cerebrovascular …

Alterations in transcriptional programs promote tumor development and progression and are
targetable by bromodomain and extraterminal (BET) protein inhibitors. However, in a multi …

Simple Summary Patients with unresectable hepatocellular carcinoma (HCC), the most
common primary tumor of the liver, have poor prognosis and are increasing worldwide. The …

Protein synthesis is a highly complex process executed by well-organized translation
machinery. Ribosomes, tRNAs and mRNAs are the principal components of this machinery …

During pregnancy, there is an intense crosstalk between mother and placenta. During the
entire time of pregnancy, the maternal system deals with a huge amount of foreign (fetal) …