Asthma and allergy are common conditions with complex etiologies involving both genetic
and environmental contributions. Recent genome‐wide association studies (GWAS) and …

Methods This paper arose from an extensive literature review undertaken in developing the
Canadian Healthy Infant Longitudinal Development (CHILD) study, a multicentre national …

Abstract Background The Hygiene Hypothesis (HH) attributes the dramatic increase in
autoimmune and allergic diseases observed in recent decades in Western countries to the …

We assessed the association between the natural environment and asthma in 49,956 New
Zealand children born in 1998 and followed up until 2016 using routinely collected data …

Background Associations of larger families with lower prevalences of hay fever, eczema and
objective markers of allergic sensitization have been found fairly consistently in affluent …

The aims of this study were to quantify and describe the variations in respiratory symptoms
and diagnosis prevalence across regions of the world according to national income. In 2002 …

Wheezing is a fairly common symptom in early childhood, but only some of these toddlers
will experience continued wheezing symptoms in later childhood. The definition of the …

Background Childhood-onset asthma (COA) has become a major and growing problem
worldwide and imposes a heavy socioeconomic burden on individuals and families; …

This comprehensive review of the recent literature was undertaken to determine the current
state of knowledge of the risk factors involved in the development of asthma in order to focus …

Objectives: To characterize whether single parent households are associated with pediatric
asthma-related repeat healthcare utilization and to examine family-level psychosocial …