Publisher Summary Studies of cytotoxicity by human lymphocytes revealed not only that
both allogeneic and syngeneic tumor cells were lysed in a non-MHC-restricted fashion, but …

The immune system is a complex system of cells and molecules that can provide us with a
basic defense against pathogenic organisms. Like the nervous system, the immune system …

We present a mathematical model of the cytotoxic T lymphocyte response to the growth of an
immunogenic tumor. The model exhibits a number of phenomena that are seen in vivo …

We present a hybrid cellular automata–partial differential equation model of moderate
complexity to describe the interactions between a growing tumor next to a nutrient source …

The dynamical basis of tumoral growth has been controversial. Many models have been
proposed to explain cancer development. The descriptions employ exponential, potential …

Influenza viruses cause a significant amount of morbidity and mortality. Understanding host
immune control efficacy and how different factors influence lung injury and disease severity …

Background. Natural killer (NK) cells may provide a first line of defense against the
metastatic implantation of circulating tumor emboli. Because tumor emboli are discharged …

Mathematical and computational models are of great help to study and predict phenomena
associated with cancer growth and development. These models may lead to introduce new …

Cytotoxic T lymphocytes (CTLs) kill virus-infected cells and tumor cells, and play a critical
role in immune protection. Our knowledge of how the CTL killing efficiency varies with CTL …

Cytotoxic T lymphocytes (CTL) help control virus infections by killing virus-infected (target)
cells. How fast do CTL find and kill target cells in vivo? Experiments allow us to follow …