The chemistry of indazole and its N-oxide derivatives is very well-known. Indazole
derivatives were extensively studied as bioactive compounds, such as anti-aggregatory and …

Abstract Chagas disease and Human African trypanosomiasis (HAT) are caused by
Trypanosoma cruzi, T. brucei rhodesiense or T. b. gambiense parasites, respectively; while …

A series of indazole N-oxide derivatives have been synthesized and their antichagasic and
leishmanocidal properties studied. 3-Cyano-2-(4-iodophenyl)-2H-indazole N1-oxide …

In the search for new therapeutic tools against Chagas' disease (American
Trypanosomiasis) two series of new platinum (II) complexes with bioactive 5-nitrofuryl …

In the search for new therapeutic tools against Chagas disease (American trypanosomiasis)
palladium and platinum complexes of the bioactive ligand pyridine-2-thiol N-oxide were …

As a continuation of our research and with the aim of obtaining new agents against Chagas
disease, an extremely neglected disease which threatens 100 million people, eighteen new …

Eight new platinum (II) complexes with 3-(5-nitrofuryl) acroleine thiosemicarbazones
showing anti-trypanosomal activity were synthesized, characterized and in vitro evaluated …

In the search for new therapeutic tools against parasitic diseases caused by the
Kinetoplastids Leishmania spp. and Trypanosoma cruzi, a novel gold (I) triphenylphosphine …

Chagas disease chemotherapy, currently based on only two drugs, nifurtimox and
benznidazole, is far from satisfactory and therefore the development of new antichagasic …

Aim The study was designed to investigate the possible anti-inflammatory activity of
indazole, its derivatives and to further investigate the possible cellular mechanisms …