Pathophysiological mechanisms and therapeutic approaches in obstructive sleep apnea syndrome
R Lv, X Liu, Y Zhang, N Dong, X Wang, Y He… - Signal transduction and …, 2023 - nature.com
Obstructive sleep apnea syndrome (OSAS) is a common breathing disorder in sleep in
which the airways narrow or collapse during sleep, causing obstructive sleep apnea. The …
which the airways narrow or collapse during sleep, causing obstructive sleep apnea. The …
Therapeutic potential of intermittent hypoxia: a matter of dose
A Navarrete-Opazo, GS Mitchell - American Journal of …, 2014 - journals.physiology.org
Intermittent hypoxia (IH) has been the subject of considerable research in recent years, and
triggers a bewildering array of both detrimental and beneficial effects in multiple …
triggers a bewildering array of both detrimental and beneficial effects in multiple …
Therapeutic acute intermittent hypoxia: A translational roadmap for spinal cord injury and neuromuscular disease
We review progress towards greater mechanistic understanding and clinical translation of a
strategy to improve respiratory and non-respiratory motor function in people with …
strategy to improve respiratory and non-respiratory motor function in people with …
[HTML][HTML] Time domains of the hypoxic ventilatory response and their molecular basis
ME Pamenter, FL Powell - Comprehensive Physiology, 2016 - ncbi.nlm.nih.gov
Ventilatory responses to hypoxia vary widely depending on the pattern and length of hypoxic
exposure. Acute, prolonged, or intermittent hypoxic episodes can increase or decrease …
exposure. Acute, prolonged, or intermittent hypoxic episodes can increase or decrease …
Hypoxic conditioning as a new therapeutic modality
S Verges, S Chacaroun, D Godin-Ribuot… - Frontiers in …, 2015 - frontiersin.org
Preconditioning refers to a procedure by which a single noxious stimulus below the
threshold of damage is applied to the tissue in order to increase resistance to the same or …
threshold of damage is applied to the tissue in order to increase resistance to the same or …
[HTML][HTML] A comprehensive review of respiratory, autonomic and cardiovascular responses to intermittent hypoxia in humans
S Puri, G Panza, JH Mateika - Experimental neurology, 2021 - Elsevier
This review explores forms of respiratory and autonomic plasticity, and associated outcome
measures, that are initiated by exposure to intermittent hypoxia. The review focuses primarily …
measures, that are initiated by exposure to intermittent hypoxia. The review focuses primarily …
Daily exposure to mild intermittent hypoxia reduces blood pressure in male patients with obstructive sleep apnea and hypertension
Rationale: Daily exposure to mild intermittent hypoxia (MIH) may elicit beneficial
cardiovascular outcomes. Objectives: To determine the effect of 15 days of MIH and in-home …
cardiovascular outcomes. Objectives: To determine the effect of 15 days of MIH and in-home …
Obstructive sleep apnea
DP White, MK Younes - Comprehensive Physiology, 2012 - Wiley Online Library
Obstructive sleep apnea (OSA) is a common disorder characterized by repetitive collapse of
the pharyngeal airway during sleep. Control of pharyngeal patency is a complex process …
the pharyngeal airway during sleep. Control of pharyngeal patency is a complex process …
Intermittent hypoxia: a low-risk research tool with therapeutic value in humans
JH Mateika, M El-Chami… - Journal of applied …, 2015 - journals.physiology.org
Intermittent hypoxia has generally been perceived as a high-risk stimulus, particularly in the
field of sleep medicine, because it is thought to initiate detrimental cardiovascular …
field of sleep medicine, because it is thought to initiate detrimental cardiovascular …
Intermittent hypoxia and respiratory plasticity in humans and other animals: does exposure to intermittent hypoxia promote or mitigate sleep apnoea?
JH Mateika, G Narwani - Experimental Physiology, 2009 - Wiley Online Library
This review focuses on two phenomena that are initiated during and after exposure to
intermittent hypoxia. The two phenomena are referred to as long‐term facilitation and …
intermittent hypoxia. The two phenomena are referred to as long‐term facilitation and …