Pulmonary fibrosis is a progressively aggravating lethal disease that is a serious public
health concern. Although the incidence of this disease is increasing, there is a lack of …

Organ fibrosis represents a dysregulated, maladaptive wound repair response that results in
progressive disruption of normal tissue architecture leading to detrimental deterioration in …

Quercetin is a flavonoid compound rich in many natural plants with a wide range of
pharmacological effects and nutritional value. Although previous studies have initially shown …

Exploitation of nanocarriers provides a compartment for enclosing drugs to protect them from
degradation and potentiate their therapeutic efficiency. In the current study, amitriptyline-and …

Hepatic stellate cells activation (HSCs) plays a crucial role in the pathogenesis of liver
fibrosis. Specific microRNAs have been suggested to affect the activation of HSCs via …

BACKGROUND Pulmonary fibrosis (PF) is a chronic interstitial lung disease characterized
by fibroblast proliferation and extracellular matrix formation, causing structural damage and …

Liver fibrosis is characterized by a series of events including activation of quiescent hepatic
stellate cells (HSCs) into proinflammatory, contractile, and fibrogenic myofibroblasts, which …

Idiopathic pulmonary fibrosis (IPF) is an interstitial lung disease with limited treatment
options. Zingerone found in ginger (Zingiber officinale L.) has many pharmacological effects …

Vanillic acid (VA) is a phenolic compound with potential antioxidant activity, which improves
ischemia-induced myocardial degeneration, by reducing oxidative stress; however, it suffers …

A condition of scarring of lung tissue due to a wide range of causes (such as environmental
pollution, cigarette smoking (CS), lung diseases, some medications, etc.) has been reported …