Vector-borne illnesses comprise a significant portion of human maladies, representing 17%
of global infections. Transmission of vector-borne pathogens to mammals primarily occurs …

Lipid droplets (LD) have long been considered as mere fat drops; however, LD have lately
been revealed to be ubiquitous, dynamic and to be present in diverse organelles in which …

Trypanosomiases and leishmaniases are neglected tropical diseases that have been
spreading to previously non-affected areas in recent years. Identification of new …

In situ visualization of lipid composition diversity in lipid droplets (LDs) is essential for
decoding lipid metabolism and function. However, effective probes for simultaneously …

The present review addresses basic aspects of the biology of the pathogenic protozoa
Trypanosoma cruzi and some comparative information of Trypanosoma brucei. Like …

Trypanosoma species are responsible for chronic and systemic infections in millions of
people around the world, compromising life quality, and family and government budgets …

Rab18 is one of the small number of conserved Rab proteins which have been traced to the
last eukaryotic common ancestor. It is found in organisms ranging from humans to …

The mechanisms underlying resistance of the Chagas disease parasite, Trypanosoma cruzi,
to current therapies are not well understood, including the role of metabolic heterogeneity …

The nonpolar lipids present in cells are mainly triacylglycerols and steryl esters. When cells
are provided with an abundance of nutrients, these storage lipids accumulate. As large …

Trypanosoma cruzi, the parasite causing Chagas disease, is a digenetic flagellated protist
that infects mammals (including humans) and reduviid insect vectors. Therefore, T. cruzi …