Pore-forming toxins (PFTs) are the most common bacterial cytotoxic proteins and are
required for virulence in a large number of important pathogens, including Streptococcus …

Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) strains are
causing a severe pandemic of mainly skin and soft tissue and occasionally fatal infections …

Practical Handbook of Microbiology, 4th edition provides basic, clear and concise
knowledge and practical information about working with microorganisms. Useful to anyone …

Summary Panton-Valentine Leukocidin (PVL) is a staphylococcal bicomponent pore-forming
toxin linked to severe invasive infections. Target-cell and species specificity of PVL are …

The ability to produce water-soluble proteins with the capacity to oligomerize and form pores
within cellular lipid bilayers is a trait conserved among nearly all forms of life, including …

The outcome of encounters between Staphylococcus (S.) aureus and its human host ranges
from life-threatening infection through allergic reactions to symptom-free colonization. The …

Methicillin-resistant Staphylococcus aureus (MRSA) poses a serious threat to worldwide
health. Historically, MRSA clones have strictly been associated with hospital settings, and …

The success of Staphylococcus aureus as a leading cause of deadly hospital-acquired and
community-acquired infections is attributed to its high-level resistance to most antibiotics …

Only recently necrotizing pneumonia was defined as a specific disease entity that is caused
by a Panton-Valentine leukocidin (PVL)-producing Staphylococcus aureus strain and is …

Staphylococcus aureus is a well-known colonizer of the human skin and nose, but also a
human pathogen that causes a wide spectrum of diseases. It is well established that S …