Messenger RNAs (mRNAs) are at the center of the central dogma of molecular biology. In
eukaryotic cells, these long ribonucleic acid polymers do not exist as naked transcripts; …

Mass spectrometry (MS) is a central analytical technique used to study proteins and
biomolecules. It measures mass‐to‐charge ratio of ions to identify and quantify molecules in …

Proteins that bind the nascent transcript exiting RNA polymerase II can regulate transcription
elongation. The essential Saccharomyces cerevisiae hnRNP protein Hrp1 is one such …

Ribonucleic acids (RNAs) involve in various physiological/pathological processes by
interacting with proteins, compounds, and other RNAs. A variety of powerful computational …

UV (ultra-violet) crosslinking with mass spectrometry (XL-MS) has been established for
identifying RNA-and DNA-binding proteins along with their domains and amino acids …

The conserved SR-like protein Npl3 promotes splicing of diverse pre-mRNAs. However, the
RNA sequence (s) recognized by the RNA Recognition Motifs (RRM1 & RRM2) of Npl3 …

Eukaryotic cells without telomerase experience progressively shorter telomeres with each
round of cell division until cell cycle arrest is initiated, leading to replicative senescence …

RNA-binding proteins are essential for gene regulation and the spatial organization of cells.
Here, we report that the yeast ribosome biogenesis factor Loc1p is an intrinsically …

Multidomain RNA binding proteins (RBPs) play a crucial role in pre-messenger RNA
splicing, nuclear mRNA assembly and export, by recognizing cis-regulatory RNA sequence …