Breastfeeding is associated with long-term wellbeing including low risks of infectious
diseases and non-communicable diseases such as asthma, cancer, autoimmune diseases …

Regulatory T (TReg) cells constitute an essential counterbalance to adaptive immune
responses. Failure to maintain appropriate TReg cell numbers or function leads to …

Regulatory T cell (Treg) therapy using recipient-derived Tregs expanded ex vivo is currently
being investigated clinically by us and others as a means of reducing allograft rejection …

Regulatory T cells (Treg) are a subpopulation of T cells that maintain tolerance to self and
limit other immune responses. They achieve this through different mechanisms including the …

Background The tumor microenvironment represents an abnormal niche containing
numerous factors, such as T cells, dendritic cells (DCs), regulatory T cells (Tregs), and …

The past three decades have seen liver transplantation becoming a major therapeutic
approach in the management of end-stage liver diseases. This is due to the dramatic …

Rheumatoid arthritis (RA) is the most common immune-mediated inflammatory disease
characterized by chronic synovitis that hardly resolves spontaneously. The current treatment …

Nucleotides and nucleosides—such as adenosine triphosphate (ATP) and adenosine—are
famous for their intracellular roles as building blocks for the genetic code or cellular energy …

Secondary lymphedema is a common postcancer treatment complication, but the underlying
pathological processes are poorly understood and no curative treatment exists. To …

Innate and adaptive immune responses can speed nigrostriatal neurodegeneration in
Parkinson's disease (PD). We posit that GM-CSF can attenuate such responses. In 1-methyl …