Smart contact lenses as wearable ophthalmic devices for disease monitoring and health management

H Seo, WG Chung, YW Kwon, S Kim, YM Hong… - Chemical …, 2023 - ACS Publications
The eye contains a complex network of physiological information and biomarkers for
monitoring disease and managing health, and ocular devices can be used to effectively …

[HTML][HTML] The role of the adaptive immune system and T cell dysfunction in neurodegenerative diseases

A DeMaio, S Mehrotra, K Sambamurti… - Journal of …, 2022 - Springer
The adaptive immune system and associated inflammation are vital in surveillance and host
protection against internal and external threats, but can secondarily damage host tissues …

Glaucoma: now and beyond

H Jayaram, M Kolko, DS Friedman, G Gazzard - The Lancet, 2023 - thelancet.com
The glaucomas are a group of conditions leading to irreversible sight loss and characterised
by progressive loss of retinal ganglion cells. Although not always elevated, intraocular …

The molecular basis of retinal ganglion cell death in glaucoma

M Almasieh, AM Wilson, B Morquette… - Progress in retinal and …, 2012 - Elsevier
Glaucoma is a group of diseases characterized by progressive optic nerve degeneration that
results in visual field loss and irreversible blindness. A crucial element in the …

Deep learning in glaucoma with optical coherence tomography: a review

AR Ran, CC Tham, PP Chan, CY Cheng, YC Tham… - Eye, 2021 - nature.com
Deep learning (DL), a subset of artificial intelligence (AI) based on deep neural networks,
has made significant breakthroughs in medical imaging, particularly for image classification …

Primary open-angle glaucoma

YH Kwon, JH Fingert, MH Kuehn… - New England Journal …, 2009 - Mass Medical Soc
Primary Open-Angle Glaucoma | New England Journal of Medicine Skip to main content The
New England Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES …

Imaging and quantifying ganglion cells and other transparent neurons in the living human retina

Z Liu, K Kurokawa, F Zhang, JJ Lee… - Proceedings of the …, 2017 - National Acad Sciences
Ganglion cells (GCs) are fundamental to retinal neural circuitry, processing photoreceptor
signals for transmission to the brain via their axons. However, much remains unknown about …

Neural remodeling in retinal degeneration

RE Marc, BW Jones, CB Watt, E Strettoi - Progress in retinal and eye …, 2003 - Elsevier
Mammalian retinal degenerations initiated by gene defects in rods, cones or the retinal
pigmented epithelium (RPE) often trigger loss of the sensory retina, effectively leaving the …

[HTML][HTML] Biomechanics of the human posterior sclera: age-and glaucoma-related changes measured using inflation testing

B Coudrillier, J Tian, S Alexander… - … & visual science, 2012 - iovs.arvojournals.org
Purpose.: The objective of this study was to measure the biomechanical response of the
human posterior sclera in vitro and to estimate the effects of age and glaucoma. Methods …

[HTML][HTML] Paracrine-mediated neuroprotection and neuritogenesis of axotomised retinal ganglion cells by human dental pulp stem cells: comparison with human bone …

B Mead, A Logan, M Berry, W Leadbeater… - PloS one, 2014 - journals.plos.org
We have investigated and compared the neurotrophic activity of human dental pulp stem
cells (hDPSC), human bone marrow-derived mesenchymal stem cells (hBMSC) and human …