Hypoxia and hepatocellular carcinoma: The therapeutic target for hepatocellular carcinoma

XZ Wu, GR Xie, D Chen - Journal of gastroenterology and …, 2007 - Wiley Online Library
Hypoxia enhances proliferation, angiogenesis, metastasis, chemoresistance, and
radioresistance of hepatocellular carcinoma (HCC); suppresses differentiation and …

Targeting the vasculature in hepatocellular carcinoma treatment: Starving versus normalizing blood supply

K Liu, X Zhang, W Xu, J Chen, J Yu… - Clinical and …, 2017 - journals.lww.com
Traditional treatments for intermediate or advanced stage hepatocellular carcinoma (HCC)
such as transarterial chemoembolization (TACE) and anti-angiogenesis therapies were …

[PDF][PDF] Long‐term outcomes of stereotactic body radiation therapy in the treatment of hepatocellular cancer as a bridge to transplantation

JK O'Connor, J Trotter, GL Davis… - Liver …, 2012 - Wiley Online Library
Hepatocellular carcinoma (HCC) is potentially curable with hepatic resection or
transplantation. Few patients are eligible for resection, and many face a long wait for donor …

Hepatocellular carcinoma: regional therapy with a magnetic targeted carrier bound to doxorubicin in a dual MR imaging/conventional angiography suite—initial …

MW Wilson, RK Kerlan Jr, NA Fidelman, AP Venook… - Radiology, 2004 - pubs.rsna.org
Four patients with inoperable hepatocellular carcinoma were treated with a magnetic
targeted carrier bound to doxorubicin (MTC-DOX) by using a joint magnetic resonance (MR) …

Hepatitis B virus X protein enhances transcriptional activity of hypoxia-inducible factor-1α through activation of mitogen-activated protein kinase pathway

YG Yoo, SH Oh, ES Park, H Cho, N Lee, H Park… - Journal of Biological …, 2003 - ASBMB
Hepatitis B virus X protein (HBx) of the hepatitis B virus was strongly implicated in
angiogenesis and metastasis during hepatocarcinogenesis. Here, we explored the …

Hepatocellular carcinoma responding to superselective transarterial chemoembolization: an issue of nodule dimension?

R Golfieri, M Renzulli, C Mosconi, L Forlani… - Journal of Vascular and …, 2013 - Elsevier
PURPOSE: To evaluate the per-nodule efficacy of superselective transarterial
chemoembolization of hepatocellular carcinomas (HCCs). MATERIALS AND METHODS …

[HTML][HTML] Nanoscale CaO2 materials for synergistic transarterial chemoembolization in a VX2 orthotopic rabbit liver cancer model

Y Wang, X He, C Zhou, Y Bai, T Li, J Liu, S Ju, C Wang… - Acta Biomaterialia, 2022 - Elsevier
Transcatheter arterial chemoembolization (TACE) is extensively used in the treatment of
hepatocellular carcinoma (HCC), but its efficacy is usually limited to secondary tumor …

Hypoxia and tumor angiogenesis in the era of hepatocellular carcinoma transarterial loco-regional treatments

M Petrillo, F Patella, F Pesapane, MB Suter… - Future …, 2018 - Taylor & Francis
This review focuses upon interactions and potential therapeutic targets in the 'vicious
cycle'between hypoxia and neoangiogenesis following treatment of hepatocellular …

[PDF][PDF] Mixed phenotype hepatocellular carcinoma after transarterial chemoembolization and liver transplantation

C Zen, Y Zen, RR Mitry, D Corbeil… - Liver …, 2011 - Wiley Online Library
We investigated the phenotype of hepatocellular carcinoma (HCC) in livers removed during
transplantation after local ablation therapy by transarterial chemoembolization (TACE). This …

Management of patients with intermediate stage hepatocellular carcinoma

D Prince, K Liu, W Xu, M Chen… - … advances in medical …, 2020 - journals.sagepub.com
Hepatocellular carcinoma (HCC) causes a significant health burden globally and its impact
is expected to increase in the coming years. Intermediate stage HCC, as defined by the …