Neutrophil to lymphocyte ratio: an emerging marker of the relationships between the immune system and diseases
A Buonacera, B Stancanelli, M Colaci… - International journal of …, 2022 - mdpi.com
Over the last 10 years, the evaluation of the neutrophil-to-lymphocyte ratio (NLR) as an
emerging marker of diseases has become a compelling field of bio-medical research …
emerging marker of diseases has become a compelling field of bio-medical research …
Neutrophils as emerging therapeutic targets
Neutrophils are the most abundant circulating leukocytes, being the first line of defence
against bacterial and fungal infections. However, neutrophils also contribute to tissue …
against bacterial and fungal infections. However, neutrophils also contribute to tissue …
Severe COVID-19 is marked by a dysregulated myeloid cell compartment
J Schulte-Schrepping, N Reusch, D Paclik, K Baßler… - Cell, 2020 - cell.com
Summary Coronavirus disease 2019 (COVID-19) is a mild to moderate respiratory tract
infection, however, a subset of patients progress to severe disease and respiratory failure …
infection, however, a subset of patients progress to severe disease and respiratory failure …
Neutrophil diversity in health and disease
C Silvestre-Roig, ZG Fridlender, M Glogauer… - Trends in …, 2019 - cell.com
New evidence has challenged the outdated dogma that neutrophils are a homogeneous
population of short-lived cells. Although neutrophil subpopulations with distinct functions …
population of short-lived cells. Although neutrophil subpopulations with distinct functions …
Cell membrane-coated mimics: a methodological approach for fabrication, characterization for therapeutic applications, and challenges for clinical translation
Cell membrane-coated (CMC) mimics are micro/nanosystems that combine an isolated cell
membrane and a template of choice to mimic the functions of a cell. The design exploits its …
membrane and a template of choice to mimic the functions of a cell. The design exploits its …
The neutrophil life cycle
Neutrophils are recognized as an essential part of the innate immune response, but an
active debate still exists regarding the life cycle of these cells. Neutrophils first differentiate in …
active debate still exists regarding the life cycle of these cells. Neutrophils first differentiate in …
Neutrophil extracellular traps and their implications in cardiovascular and inflammatory disease
J Klopf, C Brostjan, W Eilenberg… - International journal of …, 2021 - mdpi.com
Neutrophils are primary effector cells of innate immunity and fight infection by phagocytosis
and degranulation. Activated neutrophils also release neutrophil extracellular traps (NETs) …
and degranulation. Activated neutrophils also release neutrophil extracellular traps (NETs) …
The effects of neutrophil-generated hypochlorous acid and other hypohalous acids on host and pathogens
A Ulfig, LI Leichert - Cellular and Molecular Life Sciences, 2021 - Springer
Neutrophils are predominant immune cells that protect the human body against infections by
deploying sophisticated antimicrobial strategies including phagocytosis of bacteria and …
deploying sophisticated antimicrobial strategies including phagocytosis of bacteria and …
The role of reactive species on innate immunity
CMC Andrés, JM Pérez de la Lastra, CA Juan, FJ Plou… - Vaccines, 2022 - mdpi.com
This review examines the role of reactive species RS (of oxygen ROS, nitrogen RNS and
halogen RHS) on innate immunity. The importance of these species in innate immunity was …
halogen RHS) on innate immunity. The importance of these species in innate immunity was …
Whole blood immunophenotyping uncovers immature neutrophil-to-VD2 T-cell ratio as an early marker for severe COVID-19
SARS-CoV-2 is the novel coronavirus responsible for the current COVID-19 pandemic.
Severe complications are observed only in a small proportion of infected patients but the …
Severe complications are observed only in a small proportion of infected patients but the …