[HTML][HTML] Metals to combat antimicrobial resistance
Bacteria, similar to most organisms, have a love–hate relationship with metals: a specific
metal may be essential for survival yet toxic in certain forms and concentrations. Metal ions …
metal may be essential for survival yet toxic in certain forms and concentrations. Metal ions …
Nanoparticles and their antimicrobial properties against pathogens including bacteria, fungi, parasites and viruses
A Khezerlou, M Alizadeh-Sani, M Azizi-Lalabadi… - Microbial …, 2018 - Elsevier
In recent year, propagation and resistance of pathogenic microorganisms (bacteria, fungi
and virals) to common antimicrobial agents has led to serious health and food problems …
and virals) to common antimicrobial agents has led to serious health and food problems …
Leveraging disulfiram to treat cancer: Mechanisms of action, delivery strategies, and treatment regimens
Y Lu, Q Pan, W Gao, Y Pu, K Luo, B He, Z Gu - Biomaterials, 2022 - Elsevier
Disulfiram (DSF) has been used as an alcoholism drug for 70 years. Recently, it has
attracted increasing attention owing to the distinguished anticancer activity, which can be …
attracted increasing attention owing to the distinguished anticancer activity, which can be …
At the nexus of antibiotics and metals: the impact of Cu and Zn on antibiotic activity and resistance
K Poole - Trends in microbiology, 2017 - cell.com
Environmental influences on antibiotic activity and resistance can wreak havoc with in vivo
antibiotic efficacy and, ultimately, antimicrobial chemotherapy. In nature, bacteria encounter …
antibiotic efficacy and, ultimately, antimicrobial chemotherapy. In nature, bacteria encounter …
Biomedical applications of copper ionophores
V Oliveri - Coordination Chemistry Reviews, 2020 - Elsevier
Copper dyshomeostasis is associated with a plethora of diseases, supporting the possibility
of applying copper ionophores to regenerate the metal homeostasis and treat copper …
of applying copper ionophores to regenerate the metal homeostasis and treat copper …
FDA-approved thiol-reacting drugs that potentially bind into the SARS-CoV-2 main protease, essential for viral replication
N Lobo-Galo, M Terrazas-López… - Journal of …, 2021 - Taylor & Francis
Emergent novel SARS-CoV-2 is responsible for the current pandemic outbreak of severe
acute respiratory syndrome with high mortality among the symptomatic population …
acute respiratory syndrome with high mortality among the symptomatic population …
Anti-periprosthetic infection strategies: from implant surface topographical engineering to smart drug-releasing coatings
A Ghimire, J Song - ACS applied materials & interfaces, 2021 - ACS Publications
Despite advanced implant sterilization and aseptic surgical techniques, periprosthetic
bacterial infection remains a major challenge for orthopedic and dental implants. Bacterial …
bacterial infection remains a major challenge for orthopedic and dental implants. Bacterial …
Copper and antibiotics: discovery, modes of action, and opportunities for medicinal applications
AG Dalecki, CL Crawford, F Wolschendorf - Advances in microbial …, 2017 - Elsevier
Copper is a ubiquitous element in the environment as well as living organisms, with its redox
capabilities and complexation potential making it indispensable for many cellular functions …
capabilities and complexation potential making it indispensable for many cellular functions …
[HTML][HTML] The revival of dithiocarbamates: from pesticides to innovative medical treatments
L Kaul, R Süss, A Zannettino, K Richter - IScience, 2021 - cell.com
Dithiocarbamates (DTCs) have been used for various applications, including as hardening
agents in rubber manufacturing, as fungicide in agriculture, and as medications to treat …
agents in rubber manufacturing, as fungicide in agriculture, and as medications to treat …
[HTML][HTML] Non-antibiotic drug repositioning as an alternative antimicrobial approach
A Barbarossa, A Rosato, F Corbo, ML Clodoveo… - Antibiotics, 2022 - mdpi.com
The worldwide scenario of antibiotic resistance and the falling number of funds for the
development of novel antibiotics have led research efforts toward the study of specific cost …
development of novel antibiotics have led research efforts toward the study of specific cost …