The tumor microenvironment is highly complex, and immune escape is currently considered
an important hallmark of cancer, largely contributing to tumor progression and metastasis …

CC chemokines (or β-chemokines) are 28 chemotactic cytokines with an N-terminal CC
domain that play an important role in immune system cells, such as CD4+ and CD8+ …

Tailoring of chitosan through the involvement of its amino, acetamido, and hydroxy groups
can give derivatives of enhanced solubility and remarkable anticancer activity. The general …

While most studies of T lymphocytes have focused on T cells reactive to complexes of
peptide and major histocompatibility complex (MHC) proteins, many other types of T cells do …

Abstract γδ T cells are a unique and conserved population of lymphocytes that have been
the subject of a recent explosion of interest owing to their essential contributions to many …

Sixteen years ago, the Nomenclature Committee of the International Union of Pharmacology
approved a system for naming human seven-transmembrane (7TM) G protein-coupled …

The skin barrier is broadly composed of two elements—a physical barrier mostly localised in
the epidermis, and an immune barrier localised in both the dermis and epidermis. These two …

γδ T cells, αβ T cells, and B cells are present together in all but the most primitive
vertebrates, suggesting that each population contributes to host immune competence …

Summary Interleukin-23 (IL-23) and CD4+ T helper 17 (Th17) cells are thought to be critical
in psoriasis pathogenesis. Here, we report that IL-23 predominantly stimulated dermal γδ T …

Abstract Foxp3+ regulatory T (Treg) cells expressing the interleukin (IL)-33 receptor ST2
mediate tissue repair in response to IL-33. Whether Treg cells also respond to the alarmin IL …