Strategies for fermentation medium optimization: an in-depth review

V Singh, S Haque, R Niwas, A Srivastava… - Frontiers in …, 2017 - frontiersin.org
Optimization of production medium is required to maximize the metabolite yield. This can be
achieved by using a wide range of techniques from classical “one-factor-at-a-time” to …

Bacterial extracellular biopolymers: Eco-diversification, biosynthesis, technological development and commercial applications

S Pandey, VK Kannaujiya - International Journal of Biological …, 2024 - Elsevier
Synthetic polymers have been widely thriving as mega industries at a commercial scale in
various commercial sectors over the last few decades. The extensive use of synthetic …

Response Surface Methodology-Genetic Algorithm Based Medium Optimization, Purification, and Characterization of Cholesterol Oxidase from Streptomyces rimosus

A Srivastava, V Singh, S Haque, S Pandey, M Mishra… - Scientific reports, 2018 - nature.com
The applicability of the statistical tools coupled with artificial intelligence techniques was
tested to optimize the critical medium components for the production of extracellular …

Extracellular cholesterol oxidase production by Streptomyces aegyptia, in vitro anticancer activities against rhabdomyosarcoma, breast cancer cell-lines and in vivo …

NEA El-Naggar, HM Soliman, NM El-Shweihy - Scientific reports, 2018 - nature.com
In recent years, microbial cholesterol oxidases have gained great attention due to its
widespread use in medical applications for serum cholesterol determination. Streptomyces …

Unraveling arbuscular mycorrhizal fungi-induced resistance of purple branch rose (Rosa rugosa 'Zizhi') to Lymantria dispar based on metabolomics

Y Lv, F Wang, H Chen, T Zhang, J Yan, Y Hu - Biological Control, 2022 - Elsevier
Currently, people primarily rely on chemical pesticides to prevent and control insect pests,
which not only introduce problems with environmental pollution but also produce chemical …

Medium Optimization by Response Surface Methodology for Improved Cholesterol Oxidase Production by a Newly Isolated Streptomyces rochei NAM‐19 Strain

EA Elsayed… - BioMed Research …, 2020 - Wiley Online Library
Cholesterol oxidase is an alcohol oxidoreductase flavoprotein with wide biotechnological
applications. The current work describes the isolation of a potential cholesterol oxidase …

Artificial Intelligence versus Statistical Modeling and Optimization of Cholesterol Oxidase Production by using Streptomyces Sp.

L Pathak, V Singh, R Niwas, K Osama, S Khan… - PloS one, 2015 - journals.plos.org
Cholesterol oxidase (COD) is a bi-functional FAD-containing oxidoreductase which
catalyzes the oxidation of cholesterol into 4-cholesten-3-one. The wider biological functions …

Identification of cholesterol-assimilating actinomycetes strain and application of statistical modeling approaches for improvement of cholesterol oxidase production by …

NEA El-Naggar, NM El-Shweihy - BMC microbiology, 2020 - Springer
Background Cholesterol oxidase biosensors have been used to determine the level of
cholesterol in different serum and food samples. Due to a wide range of industrial and …

Characterization and overproduction of cell-associated cholesterol oxidase ChoD from Streptomyces lavendulae YAKB-15

K Yamada, A Koroleva, M Laughlin, N Oksanen… - Scientific Reports, 2019 - nature.com
Cholesterol oxidases are important enzymes with a wide range of applications from basic
research to industry. In this study, we have discovered and described the first cell-associated …

Purification, characterization and amino acid content of cholesterol oxidase produced by Streptomyces aegyptia NEAE 102

NEA El-Naggar, SF Deraz, HM Soliman, NM El-Deeb… - BMC microbiology, 2017 - Springer
Background There is an increasing demand on cholesterol oxidase for its various industrial
and clinical applications. The current research was focused on extracellular cholesterol …