Engineered tissues need a vascular network to supply cells with nutrients and oxygen after
implantation. A network that can connect to the vasculature of the patient after implantation …

Enabling angiogenesis is critical for the success of tissue repair therapies and the fate of
tissue-engineered constructs. Although many biochemical signaling molecules have been …

Despite the steady increase in the number of studies focusing on the development of tissue
engineered constructs, solutions delivered to the clinic are still limited. Specifically, the lack …

Many approaches have been made toward the development of scaffolds with good
biocompatibility and appreciable physicochemical properties to facilitate stem cell adhesion …

This review focuses on vascularization and strategies involved in its evaluation and
modulation. Clinical issues associated with engineered tissues of an atomically relevant size …

Extracellular vesicles (EVs) have recently gained significant attention as important mediators
of intercellular communication, potential drug carriers, and disease biomarkers. These …

Extracellular vesicles (EVs) are natural nanoparticles that play important roles in intercellular
communication and are increasingly studied for biosignalling, pathogenesis and therapy …

Tissue organoids hold enormous potential as tools for a variety of applications, including
disease modeling and drug screening. To effectively mimic the native tissue environment, it …

The reconstruction of large skeletal defects is still a tricky challenge in orthopedics. The
newly formed bone tissue migrates sluggishly from the periphery to the center of the scaffold …

Bacterial nanocellulose (BNC) is a natural polysaccharide synthesized principally by
Komagataeibatacter xylinus which can be formed into tubes and other shapes through the …