Whole-genome sequencing of bacterial pathogens: the future of nosocomial outbreak analysis

S Quainoo, JPM Coolen, SAFT van Hijum… - Clinical microbiology …, 2017 - Am Soc Microbiol
Outbreaks of multidrug-resistant bacteria present a frequent threat to vulnerable patient
populations in hospitals around the world. Intensive care unit (ICU) patients are particularly …

[HTML][HTML] Vancomycin-resistant Enterococcus faecium and the emergence of new sequence types associated with hospital infection

RF O'Toole, KWC Leong, V Cumming… - Research in …, 2023 - Elsevier
Enterococcus faecium is a major species in infections by vancomycin-resistant enterococci
(VRE). New variants of the pathogen have emerged and become dominant in healthcare …

Rapid, comprehensive, and affordable mycobacterial diagnosis with whole-genome sequencing: a prospective study

LJ Pankhurst, C del Ojo Elias, AA Votintseva… - The Lancet …, 2016 - thelancet.com
Background Slow and cumbersome laboratory diagnostics for Mycobacterium tuberculosis
complex (MTBC) risk delayed treatment and poor patient outcomes. Whole-genome …

Artificial Intelligence and Machine learning based prediction of resistant and susceptible mutations in Mycobacterium tuberculosis

S Jamal, M Khubaib, R Gangwar, S Grover, A Grover… - Scientific reports, 2020 - nature.com
Tuberculosis (TB), an infectious disease caused by Mycobacterium tuberculosis (M. tb),
causes highest number of deaths globally for any bacterial disease necessitating novel …

Clinical value of whole-genome sequencing of Mycobacterium tuberculosis

HE Takiff, O Feo - The Lancet Infectious Diseases, 2015 - thelancet.com
Whole-genome sequencing (WGS) is now common as a result of new technologies that can
rapidly sequence a complete bacterial genome for US $500 or less. Many studies have …

[HTML][HTML] 全基因组测序与生物信息学分析在细菌耐药性研究中的应用

沈应博, 史晓敏, 沈建忠, 汪洋, 王少林 - 生物工程学报, 2019 - cjb.ijournals.cn
随着耐药细菌的大量出现及广泛传播, 细菌耐药性成为全球备受关注的问题.
耐药细菌的特征如耐药基因, 毒力因子, 质粒分型等以及不同菌株间亲缘关系对于细菌耐药性 …

Molecular epidemiology of cattle tuberculosis in Mexico through whole-genome sequencing and spoligotyping

CA Perea Razo, E Rodriguez Hernandez, SIR Ponce… - PLoS …, 2018 - journals.plos.org
Mycobacterium bovis infection in cattle persists in Mexico, posing a threat to human health.
Control of bovine tuberculosis, through the National Program Against Bovine Tuberculosis …

A bioinformatics pipeline for Mycobacterium tuberculosis sequencing that cleans contaminant reads from sputum samples

B Cuevas-Córdoba, C Fresno, JI Haase-Hernández… - PLoS …, 2021 - journals.plos.org
Next-Generation Sequencing (NGS) is widely used to investigate genomic variation. In
several studies, the genetic variation of Mycobacterium tuberculosis has been analyzed in …

Artificial intelligence and metagenomics in intestinal diseases

Y Lin, G Wang, J Yu, JJY Sung - Journal of Gastroenterology …, 2021 - Wiley Online Library
Gut microbiota has been shown to associate with the development of gastrointestinal
diseases. In the last decade, development in whole metagenome sequencing and 16S …

Lineage classification and antitubercular drug resistance surveillance of Mycobacterium tuberculosis by whole-genome sequencing in Southern India

M Rao, K Wollenberg, M Harris, S Kulavalli… - Microbiology …, 2023 - Am Soc Microbiol
Whole-genome sequencing has created a revolution in tuberculosis management by
providing a comprehensive picture of the various genetic polymorphisms with …