Metastasis
S Gerstberger, Q Jiang, K Ganesh - Cell, 2023 - cell.com
Most cancer-associated deaths occur due to metastasis, yet our understanding of metastasis
as an evolving, heterogeneous, systemic disease and of how to effectively treat it is still …
as an evolving, heterogeneous, systemic disease and of how to effectively treat it is still …
Thermal immuno-nanomedicine in cancer
Immunotherapy has revolutionized the treatment of patients with cancer. However,
promoting antitumour immunity in patients with tumours that are resistant to these therapies …
promoting antitumour immunity in patients with tumours that are resistant to these therapies …
Dostarlimab for primary advanced or recurrent endometrial cancer
MR Mirza, DM Chase, BM Slomovitz… - … England Journal of …, 2023 - Mass Medical Soc
Background Dostarlimab is an immune-checkpoint inhibitor that targets the programmed cell
death 1 receptor. The combination of chemotherapy and immunotherapy may have …
death 1 receptor. The combination of chemotherapy and immunotherapy may have …
Advances in immunotherapy for triple-negative breast cancer
Y Liu, Y Hu, J Xue, J Li, J Yi, J Bu, Z Zhang, P Qiu… - Molecular cancer, 2023 - Springer
Background Immunotherapy has recently emerged as a treatment strategy which stimulates
the human immune system to kill tumor cells. Tumor immunotherapy is based on immune …
the human immune system to kill tumor cells. Tumor immunotherapy is based on immune …
Immune checkpoint therapy for solid tumours: clinical dilemmas and future trends
Q Sun, Z Hong, C Zhang, L Wang, Z Han… - Signal transduction and …, 2023 - nature.com
Abstract Immune-checkpoint inhibitors (ICBs), in addition to targeting CTLA-4, PD-1, and PD-
L1, novel targeting LAG-3 drugs have also been approved in clinical application. With the …
L1, novel targeting LAG-3 drugs have also been approved in clinical application. With the …
Towards targeting the breast cancer immune microenvironment
The tumour immune microenvironment is shaped by the crosstalk between cancer cells,
immune cells, fibroblasts, endothelial cells and other stromal components. Although the …
immune cells, fibroblasts, endothelial cells and other stromal components. Although the …
Advances in systemic therapies for triple negative breast cancer
RA Leon-Ferre, MP Goetz - Bmj, 2023 - bmj.com
Triple negative breast cancer (TNBC) continues to be the subtype of breast cancer with the
highest rates of recurrence and mortality. The lack of expression of targetable proteins such …
highest rates of recurrence and mortality. The lack of expression of targetable proteins such …
The complementarity of DDR, nucleic acids and anti-tumour immunity
Immune checkpoint blockade (ICB) immunotherapy is a first-line treatment for selected
cancers, yet the mechanisms of its efficacy remain incompletely understood. Furthermore …
cancers, yet the mechanisms of its efficacy remain incompletely understood. Furthermore …
[HTML][HTML] Intratumoral CD8+ T cells with a tissue-resident memory phenotype mediate local immunity and immune checkpoint responses in breast cancer
B Virassamy, F Caramia, P Savas, S Sant, J Wang… - Cancer Cell, 2023 - cell.com
CD8+ tumor-infiltrating lymphocytes with a tissue-resident memory T (T RM) cell phenotype
are associated with favorable prognosis in patients with triple-negative breast cancer …
are associated with favorable prognosis in patients with triple-negative breast cancer …
Immunotherapy approaches for breast cancer patients in 2023
Immunotherapy, particularly agents targeting the immunoregulatory PD-1/PD-L1 axis,
harnesses the power of the immune system to treat cancer, with unique potential for a …
harnesses the power of the immune system to treat cancer, with unique potential for a …