The interaction between nanoparticles and immune system: application in the treatment of inflammatory diseases

J Liu, Z Liu, Y Pang, H Zhou - Journal of Nanobiotechnology, 2022 - Springer
Nanoparticle (NP) is an emerging tool applied in the biomedical field. With combination of
different materials and adjustment of their physical and chemical properties, nanoparticles …

The design of poly (lactide-co-glycolide) nanocarriers for medical applications

D Essa, PPD Kondiah, YE Choonara… - … in bioengineering and …, 2020 - frontiersin.org
Polymeric biomaterials have found widespread applications in nanomedicine, and poly
(lactide-co-glycolide),(PLGA) in particular has been successfully implemented in numerous …

Injectable hydrogels with high drug loading through B–N coordination and ROS-triggered drug release for efficient treatment of chronic periodontitis in diabetic rats

X Zhao, Y Yang, J Yu, R Ding, D Pei, Y Zhang, G He… - Biomaterials, 2022 - Elsevier
The clinical management of chronic periodontitis with diabetes mellitus (CPDM) is a long-
standing thorny issue. The excessive production of reactive oxygen species (ROS) is one of …

Biomedical applications of polysaccharide nanoparticles for chronic inflammatory disorders: Focus on rheumatoid arthritis, diabetes and organ fibrosis

P Allawadhi, V Singh, K Govindaraj, I Khurana… - Carbohydrate …, 2022 - Elsevier
Polysaccharides are biopolymers distinguished by their complex secondary structures
executing various roles in microorganisms, plants, and animals. They are made up of long …

Local delivery and controlled release drugs systems: a new approach for the clinical treatment of periodontitis therapy

M Amato, S Santonocito, A Polizzi, GM Tartaglia… - Pharmaceutics, 2023 - mdpi.com
Periodontitis is an inflammatory disease of the gums characterized by the degeneration of
periodontal ligaments, the formation of periodontal pockets, and the resorption of the …

Local drug delivery systems as therapeutic strategies against periodontitis: A systematic review

Y Wei, Y Deng, S Ma, M Ran, Y Jia, J Meng… - Journal of Controlled …, 2021 - Elsevier
Periodontitis is a chronic inflammation of the soft tissue surrounding and supporting the
teeth, which causes periodontal structural damage, alveolar bone resorption, and even tooth …

Gut microbiota may mediate the influence of periodontitis on prediabetes

L Li, J Bao, Y Chang, M Wang… - Journal of Dental …, 2021 - journals.sagepub.com
Mounting evidence has shown that periodontitis is associated with diabetes. However, a
causal relationship remains to be determined. Recent studies reported that periodontitis may …

Nanoparticles in dentistry: A comprehensive review

G Moraes, C Zambom, WL Siqueira - Pharmaceuticals, 2021 - mdpi.com
In recent years, nanoparticles (NPs) have been receiving more attention in dentistry. Their
advantageous physicochemical and biological properties can improve the diagnosis …

Metformin-loaded polymer-based microbubbles/nanoparticles generated for the treatment of type 2 diabetes mellitus

S Cesur, ME Cam, FS Sayın, S Su, A Harker… - Langmuir, 2021 - ACS Publications
Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease that is increasingly common
all over the world with a high risk of progressive hyperglycemia and high microvascular and …

Metformin carbon dots for promoting periodontal bone regeneration via activation of ERK/AMPK pathway

C Ren, X Hao, L Wang, Y Hu, L Meng… - Advanced …, 2021 - Wiley Online Library
The osteogenic potential of mesenchymal stem cells (MSCs) is severely impaired under
persistent inflammation of periodontitis. A highly efficient way to promote or rescue …