Targeting cell death pathways for cancer therapy: recent developments in necroptosis, pyroptosis, ferroptosis, and cuproptosis research
X Tong, R Tang, M Xiao, J Xu, W Wang… - Journal of hematology & …, 2022 - Springer
Many types of human cells self-destruct to maintain biological homeostasis and defend the
body against pathogenic substances. This process, called regulated cell death (RCD), is …
body against pathogenic substances. This process, called regulated cell death (RCD), is …
Apoptotic cell death in disease—Current understanding of the NCCD 2023
I Vitale, F Pietrocola, E Guilbaud… - Cell Death & …, 2023 - nature.com
Apoptosis is a form of regulated cell death (RCD) that involves proteases of the caspase
family. Pharmacological and genetic strategies that experimentally inhibit or delay apoptosis …
family. Pharmacological and genetic strategies that experimentally inhibit or delay apoptosis …
Autophagy in major human diseases
Autophagy is a core molecular pathway for the preservation of cellular and organismal
homeostasis. Pharmacological and genetic interventions impairing autophagy responses …
homeostasis. Pharmacological and genetic interventions impairing autophagy responses …
Heme oxgenase-1, a cardinal modulator of regulated cell death and inflammation
SW Ryter - Cells, 2021 - mdpi.com
Heme oxygenase catalyzes the rate-limiting step in heme degradation in order to generate
biliverdin, carbon monoxide (CO), and iron. The inducible form of the enzyme, heme …
biliverdin, carbon monoxide (CO), and iron. The inducible form of the enzyme, heme …
Immunogenic cell death in cancer: concept and therapeutic implications
Mammalian cells responding to specific perturbations of homeostasis can undergo a
regulated variant of cell death that elicits adaptive immune responses. As immunogenic cell …
regulated variant of cell death that elicits adaptive immune responses. As immunogenic cell …
[HTML][HTML] Signal pathways in the treatment of Alzheimer's disease with traditional Chinese medicine
MR Ding, YJ Qu, B Hu, HM An - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Aim of the review This study aimed to reveal the classical signal pathways and important
potential targets of traditional Chinese medicine (TCM) for treating Alzheimer's disease (AD) …
potential targets of traditional Chinese medicine (TCM) for treating Alzheimer's disease (AD) …
Multi-walled carbon nanotubes trigger lysosome-dependent cell death (pyroptosis) in macrophages but not in neutrophils
Carbon nanotubes (CNTs) have been extensively investigated, and several studies have
shown that multi-walled CNTs can trigger inflammation and fibrosis in animal models …
shown that multi-walled CNTs can trigger inflammation and fibrosis in animal models …
Autophagy‑regulating miRNAs: Novel therapeutic targets for Parkinson's disease
Z Ma, H Liang, B Hu, S Cai… - … journal of molecular …, 2023 - spandidos-publications.com
Parkinson's disease (PD) is a neurodegenerative disorder that has a high incidence during
the aging process and is characterized by the loss of dopaminergic neurons in the …
the aging process and is characterized by the loss of dopaminergic neurons in the …
Targeting autophagy in thyroid cancer: EMT, apoptosis, and cancer stem cells
TM Holm, S Yeo, KM Turner, JL Guan - Frontiers in Cell and …, 2022 - frontiersin.org
Autophagy is a highly conserved recycling process through which cellular homeostasis is
achieved and maintained. With respect to cancer biology, autophagy acts as a double …
achieved and maintained. With respect to cancer biology, autophagy acts as a double …
Review of cancer cell resistance mechanisms to apoptosis and actual targeted therapies
M Kulbay, A Paimboeuf, D Ozdemir… - Journal of Cellular …, 2022 - Wiley Online Library
The apoptosis pathway is a programmed cell death mechanism that is crucial for cellular
and tissue homeostasis and organ development. There are three major caspase‐dependent …
and tissue homeostasis and organ development. There are three major caspase‐dependent …