Sex and the development of Alzheimer's disease
CJ Pike - Journal of neuroscience research, 2017 - Wiley Online Library
Men and women exhibit differences in the development and progression of Alzheimer's
disease (AD). The factors underlying the sex differences in AD are not well understood. This …
disease (AD). The factors underlying the sex differences in AD are not well understood. This …
Endogenous and exogenous estrogen exposures: how women's reproductive health can drive brain aging and inform Alzheimer's prevention
S Jett, N Malviya, E Schelbaum, G Jang… - Frontiers in Aging …, 2022 - frontiersin.org
After advanced age, female sex is the major risk factor for late-onset Alzheimer's disease
(AD), the most common cause of dementia affecting over 24 million people worldwide. The …
(AD), the most common cause of dementia affecting over 24 million people worldwide. The …
Sex differences in Alzheimer's disease and common neuropathologies of aging
Alzheimer's dementia is significantly more common in women than in men. However, few
pathological studies have addressed sex difference in Alzheimer's disease (AD) and other …
pathological studies have addressed sex difference in Alzheimer's disease (AD) and other …
Sex-specific association of apolipoprotein E with cerebrospinal fluid levels of tau
Importance The strongest genetic risk factor for Alzheimer disease (AD), the apolipoprotein
E (APOE) gene, has a stronger association among women compared with men. Yet limited …
E (APOE) gene, has a stronger association among women compared with men. Yet limited …
Sex differences in the association between AD biomarkers and cognitive decline
Women are disproportionately affected by Alzheimer's disease (AD) in terms of both disease
prevalence and severity. Previous autopsy work has suggested that, in the presence of AD …
prevalence and severity. Previous autopsy work has suggested that, in the presence of AD …
Cognition, mood and sleep in menopausal transition: the role of menopause hormone therapy
G Gava, I Orsili, S Alvisi, I Mancini, R Seracchioli… - Medicina, 2019 - mdpi.com
During the menopausal transition, which begins four to six years before cessation of
menses, middle-aged women experience a progressive change in ovarian activity and a …
menses, middle-aged women experience a progressive change in ovarian activity and a …
[图书][B] The female brain
L Brizendine - 2007 - books.google.com
Since Dr. Brizendine wrote The Female Brain ten years ago, the response has been
overwhelming. This New York Times bestseller has been translated into more than thirty …
overwhelming. This New York Times bestseller has been translated into more than thirty …
Is hormone replacement therapy a risk factor or a therapeutic option for Alzheimer's disease?
ZB Mills, RLM Faull, A Kwakowsky - International Journal of Molecular …, 2023 - mdpi.com
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that accounts for
more than half of all dementia cases in the elderly. Interestingly, the clinical manifestations of …
more than half of all dementia cases in the elderly. Interestingly, the clinical manifestations of …
Systematic review and meta-analysis of the effects of menopause hormone therapy on risk of Alzheimer's disease and dementia
M Nerattini, S Jett, C Andy, C Carlton… - Frontiers in aging …, 2023 - frontiersin.org
Introduction Despite a large preclinical literature demonstrating neuroprotective effects of
estrogen, use of menopausal hormone therapy (HT) for Alzheimer's disease (AD) risk …
estrogen, use of menopausal hormone therapy (HT) for Alzheimer's disease (AD) risk …
Neurotrophic and neuroprotective actions of estrogen: basic mechanisms and clinical implications
Estrogen is an important hormone signal that regulates multiple tissues and functions in the
body. This review focuses on the neurotrophic and neuroprotective actions of estrogen in the …
body. This review focuses on the neurotrophic and neuroprotective actions of estrogen in the …