Metabolic engineering: methodologies and applications

MJ Volk, VG Tran, SI Tan, S Mishra, Z Fatma… - Chemical …, 2022 - ACS Publications
Metabolic engineering aims to improve the production of economically valuable molecules
through the genetic manipulation of microbial metabolism. While the discipline is a little over …

Recent advancements in astaxanthin production from microalgae: A review

AK Patel, VS Tambat, CW Chen, AS Chauhan… - Bioresource …, 2022 - Elsevier
Microalgae have emerged as the best source of high-value astaxanthin producers. Algal
astaxanthin possesses numerous bioactivities hence the rising demand for several health …

Metabolic engineering and synthetic biology strategies for producing high-value natural pigments in Microalgae

K Cao, Y Cui, F Sun, H Zhang, J Fan, B Ge, Y Cao… - Biotechnology …, 2023 - Elsevier
Microalgae are microorganisms capable of producing bioactive compounds using
photosynthesis. Microalgae contain a variety of high value-added natural pigments such as …

[HTML][HTML] Optimization of microbial cell factories for astaxanthin production: Biosynthesis and regulations, engineering strategies and fermentation optimization …

M Basiony, L Ouyang, D Wang, J Yu, L Zhou… - Synthetic and Systems …, 2022 - Elsevier
The global market demand for natural astaxanthin is rapidly increasing owing to its safety,
the potential health benefits, and the diverse applications in food and pharmaceutical …

Advances in the synthesis of three typical tetraterpenoids including β-carotene, lycopene and astaxanthin

Y Jing, Y Wang, D Zhou, J Wang, J Li, J Sun… - Biotechnology …, 2022 - Elsevier
Carotenoids are natural pigments that widely exist in nature. Due to their excellent
antioxidant, anticancer and anti-inflammatory properties, carotenoids are commonly used in …

Metabolic engineering for sustainability and health

GB Kim, SY Choi, IJ Cho, DH Ahn, SY Lee - Trends in Biotechnology, 2023 - cell.com
Bio-based production of chemicals and materials has attracted much attention due to the
urgent need to establish sustainability and enhance human health. Metabolic engineering …

Production of High Levels of 3S,3′S-Astaxanthin in Yarrowia lipolytica via Iterative Metabolic Engineering

HZ Zhu, S Jiang, JJ Wu, XR Zhou, PY Liu… - Journal of Agricultural …, 2022 - ACS Publications
Astaxanthin is a highly value-added keto-carotenoid compound. The astaxanthin 3 S, 3′ S-
isomer is more desirable for food additives, cosmetics, and pharmaceuticals due to health …

Generative artificial intelligence GPT-4 accelerates knowledge mining and machine learning for synthetic biology

Z Xiao, W Li, H Moon, GW Roell, Y Chen… - ACS synthetic …, 2023 - ACS Publications
Knowledge mining from synthetic biology journal articles for machine learning (ML)
applications is a labor-intensive process. The development of natural language processing …

Metabolic Engineering of Yarrowia lipolytica for Terpenoid Production: Tools and Strategies

TL Zhang, HW Yu, LD Ye - ACS Synthetic Biology, 2023 - ACS Publications
Terpenoids are a diverse group of compounds with isoprene units as basic building blocks.
They are widely used in the food, feed, pharmaceutical, and cosmetic industries due to their …

Cannabis sativa: origin and history, glandular trichome development, and cannabinoid biosynthesis

Z Xie, Y Mi, L Kong, M Gao, S Chen… - Horticulture …, 2023 - academic.oup.com
Is Cannabis a boon or bane? Cannabis sativa has long been a versatile crop for fiber
extraction (industrial hemp), traditional Chinese medicine (hemp seeds), and recreational …