Suramin was the first urea-based drug to be approved in clinic, and in the following century
a number of milestone drugs based on this scaffold were developed. Indeed, urea soon …

Six benzimidazole derivatives have been synthesized and characterized using
spectroscopic techniques such as IR, 1 H NMR, 13 C NMR, and mass spectrometry. The …

Heterocyclic molecules have fascinated a massive interest in medicinal chemistry. They are
heterocyclic compounds that have gained significance due to their diverse variety of …

Designing new compounds from existing chemotherapeutic drugs to enhance inhibitory
effects on tumor cells while overcoming multidrug resistance is one of the important …

This study focuses on the efficient synthesis of series of substituted 4-amino-6-(1H-
benzimidazol-2-ylsulfanyl) benzene-1, 3-dicarbonitrile derivatives synthesized from …

The chemical reaction of 4-bromobenzoylchloride and 2-aminothiazole in the presence of
potassium thiocyanate yielded a white solid formulated as C15H10BrN3OS2, which consists …

(Acryloyl) thioureido) benzoic acid) derivative 3a-c was obtained by reacting cinnamoyl
isothiocyanate 2a-c with 2-aminobenzoic acid 1. The cyclization of thiourea 3a-c in dry …

Monosubstituted thioureas have found wide application in various fields of science and
technology. They are widely used in organic synthesis to obtain various heterocyclic and …

Thiourea is a carbon, hydrogen, sulphur, and nitrogen-based organic molecule. The
thiourea group has been improved by replacing various substituents for its hydrogen atoms …