Objective To review biomarker discovery studies using omics data for patient stratification
which led to clinically validated FDA-cleared tests or laboratory developed tests, in order to …

Cancer is a global health issue as a multi-factorial complex disease, and early detection and
novel therapeutic strategies are required for more effective cancer management. With the …

Adjuvant radiotherapy after prostatectomy was recently challenged by early salvage
radiotherapy, which highlighted the need for biomarkers to improve risk stratification …

Prostate cancer that recurs following androgen-deprivation therapy is termed castration-
resistant, which is incurable and is marked by reactivation of androgen receptor (AR) …

Abstract Context Prostate cancer (PCa) is the most common solid organ malignancy in men
and is the third leading cause of cancer death. Accurate methods for the detection and …

Background Neuroendocrine prostate cancer (NEPC) may be rising in prevalence as
patients with advanced prostate cancer potentially develop resistance to contemporary anti …

Purpose: Prostatectomy is one of the main therapeutic options for prostate cancer (PCa).
Studies proved the benefit of adjuvant radiotherapy (aRT) on clinical outcomes, with more …

Simple Summary In patients with prostate cancer, lymph node involvement is a risk factor of
relapse. Current guidelines recommend extended lymph node dissection to better stage the …

MRI is used to image prostate cancer and target tumors for biopsy or therapeutic ablation.
The objective was to understand the biology of tumors not visible on MRI that may go …

Context Multiparametric magnetic resonance imaging (mpMRI) detects most, but not all,
clinically significant prostate cancer. The genetic basis of prostate cancer visibility and …