Wastewater-based epidemiology biomarkers: past, present and future

PM Choi, BJ Tscharke, E Donner, JW O'Brien… - TrAC Trends in …, 2018 - Elsevier
Wastewater is a complex matrix containing a wide range of chemical and biological markers
of human activity. Relating concentrations of these “waste” materials in wastewater influent …

A systematic review of adverse events arising from the use of synthetic cannabinoids and their associated treatment

RJ Tait, D Caldicott, D Mountain, SL Hill… - Clinical …, 2016 - Taylor & Francis
Abstract Context: Synthetic cannabinoids (SCs) such as “Spice”,“K2”, etc. are widely
available via the internet despite increasing legal restrictions. Currently, the prevalence of …

Khat and synthetic cathinones: a review

MJ Valente, P Guedes de Pinho… - Archives of …, 2014 - Springer
For centuries,'khat sessions' have played a key role in the social and cultural traditions
among several communities around Saudi Arabia and most East African countries. The …

The pharmacology and toxicology of kratom: from traditional herb to drug of abuse

ML Warner, NC Kaufman, O Grundmann - International journal of legal …, 2016 - Springer
Mitragyna speciosa (Rubiaceae), commonly known as kratom, is a tropical tree with a long
history of traditional use in parts of Africa and Southeast Asia. In recent years, kratom has …

The adverse health effects of synthetic cannabinoids with emphasis on psychosis-like effects

J Van Amsterdam, T Brunt… - Journal of …, 2015 - journals.sagepub.com
Cannabis use is associated with an increased risk of psychosis in vulnerable individuals.
Cannabis containing high levels of the partial cannabinoid receptor subtype 1 (CB1) agonist …

Acute effects of synthetic cannabinoids: Update 2015

J Tournebize, V Gibaja, JP Kahn - Substance abuse, 2017 - journals.sagepub.com
Background Cannabis is the most widely used illicit drug in the United States and Europe. In
recent years, a range of new substances with cannabis-like effects—known as synthetic …

Psychosis and synthetic cannabinoids

H Deng, CD Verrico, TR Kosten, DA Nielsen - Psychiatry Research, 2018 - Elsevier
Synthetic cannabinoid (SC) products have gained popularity as abused drugs over the past
decade in many countries. The SCs broadly impact psychological state (eg, mood, suicidal …

Cytotoxicity of synthetic cannabinoids on primary neuronal cells of the forebrain: the involvement of cannabinoid CB1 receptors and apoptotic cell death

K Tomiyama, M Funada - Toxicology and applied pharmacology, 2014 - Elsevier
The abuse of herbal products containing synthetic cannabinoids has become an issue of
public concern. The purpose of this paper was to evaluate the acute cytotoxicity of synthetic …

The synthesis and pharmacological evaluation of adamantane-derived indoles: cannabimimetic drugs of abuse

SD Banister, SM Wilkinson, M Longworth… - ACS chemical …, 2013 - ACS Publications
Two novel adamantane derivatives, adamantan-1-yl (1-pentyl-1 H-indol-3-yl) methanone
(AB-001) and N-(adamtan-1-yl)-1-pentyl-1 H-indole-3-carboxamide (SDB-001), were …

New and emerging illicit psychoactive substances

R Graddy, ME Buresh, DA Rastegar - Medical Clinics, 2018 - medical.theclinics.com
A 28-year-old man is evaluated by emergency medical technicians after a bystander calls
911 for concern about altered mental status. On arrival, the man is slow to respond to …