Over the last three decades, polymeric micelles have emerged as a highly promising drug
delivery platform for therapeutic compounds. Particularly, poorly soluble small molecules …

The lack of efficient therapeutic options for many severe disorders including cancer spurs
demand for improved drug delivery technologies. Nanoscale drug delivery systems based …

An autologous bone graft is still the ideal material for the repair of craniofacial defects, but its
availability is limited and harvesting can be associated with complications. Bone …

Docking is a computational technique that places a small molecule (ligand) in the binding
site of its macromolecular target (receptor) and estimates its binding affinity. This review …

Cancer is the second leading cause of death in the United States. Conventional therapies
cause widespread systemic toxicity and lead to serious side effects which prohibit their long …

Highlights•PDC a promising strategy to improve solubilization and drug targeting.•Natural
and synthetic polymers as building blocks of PDC.•Polymer and polysaccharide using graft …

Adagen, an enzyme replacement treatment for adenosine deaminase deficiency, was the
first protein-polymer conjugate to be approved in early 1990 s. Post this regulatory approval …

The drug-loading properties of nanocarriers depend on the chemical structures and
properties of their building blocks. Here we customize telodendrimers (linear dendritic …

The nanoparticle delivery system is one of the promising nanotechnology applications for
efficient drug delivery to the targeted site. However, the selection of lead excipient …

Introduction: After more than four decades of intense research, oral controlled drug delivery
systems (DDSs) still represent a topic of major interest for pharmaceutical scientist and …