Mitochondrial dynamics in health and disease: mechanisms and potential targets
W Chen, H Zhao, Y Li - Signal transduction and targeted therapy, 2023 - nature.com
Mitochondria are organelles that are able to adjust and respond to different stressors and
metabolic needs within a cell, showcasing their plasticity and dynamic nature. These …
metabolic needs within a cell, showcasing their plasticity and dynamic nature. These …
Amyloid β-based therapy for Alzheimer's disease: Challenges, successes and future
Y Zhang, H Chen, R Li, K Sterling… - Signal transduction and …, 2023 - nature.com
Amyloid β protein (Aβ) is the main component of neuritic plaques in Alzheimer's disease
(AD), and its accumulation has been considered as the molecular driver of Alzheimer's …
(AD), and its accumulation has been considered as the molecular driver of Alzheimer's …
Recent advances in Alzheimer's disease: Mechanisms, clinical trials and new drug development strategies
J Zhang, Y Zhang, J Wang, Y Xia, J Zhang… - Signal transduction and …, 2024 - nature.com
Alzheimer's disease (AD) stands as the predominant form of dementia, presenting significant
and escalating global challenges. Its etiology is intricate and diverse, stemming from a …
and escalating global challenges. Its etiology is intricate and diverse, stemming from a …
[HTML][HTML] Mitochondrial fusion and fission: The fine-tune balance for cellular homeostasis
M Adebayo, S Singh, AP Singh… - FASEB journal: official …, 2021 - ncbi.nlm.nih.gov
Mitochondria are highly dynamic, maternally inherited cytoplasmic organelles, which fulfill
cellular energy demand through the oxidative phosphorylation system. Besides, they play an …
cellular energy demand through the oxidative phosphorylation system. Besides, they play an …
Mitochondria dysfunction in the pathogenesis of Alzheimer's disease: Recent advances
Alzheimer's disease (AD) is one of the most prevalent neurodegenerative diseases,
characterized by impaired cognitive function due to progressive loss of neurons in the brain …
characterized by impaired cognitive function due to progressive loss of neurons in the brain …
The cell biology of mitochondrial membrane dynamics
M Giacomello, A Pyakurel, C Glytsou… - Nature reviews Molecular …, 2020 - nature.com
Owing to their ability to efficiently generate ATP required to sustain normal cell function,
mitochondria are often considered the 'powerhouses of the cell'. However, our …
mitochondria are often considered the 'powerhouses of the cell'. However, our …
The role of mitochondrial fission in cardiovascular health and disease
JM Quiles, ÅB Gustafsson - Nature Reviews Cardiology, 2022 - nature.com
Mitochondria are organelles involved in the regulation of various important cellular
processes, ranging from ATP generation to immune activation. A healthy mitochondrial …
processes, ranging from ATP generation to immune activation. A healthy mitochondrial …
Mitochondrial dynamics: overview of molecular mechanisms
L Tilokani, S Nagashima, V Paupe… - Essays in …, 2018 - portlandpress.com
Mitochondria are highly dynamic organelles undergoing coordinated cycles of fission and
fusion, referred as 'mitochondrial dynamics', in order to maintain their shape, distribution and …
fusion, referred as 'mitochondrial dynamics', in order to maintain their shape, distribution and …
Mitophagy, mitochondrial homeostasis, and cell fate
K Ma, G Chen, W Li, O Kepp, Y Zhu… - Frontiers in cell and …, 2020 - frontiersin.org
Mitochondria are highly plastic and dynamic organelles that have graded responses to the
changing cellular, environmental, and developmental cues. Mitochondria undergo constant …
changing cellular, environmental, and developmental cues. Mitochondria undergo constant …
[HTML][HTML] Mechanistic insights and perspectives involved in neuroprotective action of quercetin
Neurodegenerative diseases (NDDs) are the primary cause of disabilities in the elderly
people. Growing evidence indicates that oxidative stress, mitochondrial dysfunction …
people. Growing evidence indicates that oxidative stress, mitochondrial dysfunction …