Time to abandon single-site irradiation for inducing abscopal effects

ED Brooks, JY Chang - Nature reviews Clinical oncology, 2019 - nature.com
Considerable interest is being directed toward combining immune-checkpoint inhibition (ICI)
with radiotherapy to improve response rates to ICI, which have been disappointingly low at …

Targeting hallmarks of cancer to enhance radiosensitivity in gastrointestinal cancers

AM Buckley, N Lynam-Lennon, H O'Neill… - Nature reviews …, 2020 - nature.com
Radiotherapy is used in the treatment of approximately 50% of all malignancies including
gastrointestinal cancers. Radiation can be given prior to surgery (neoadjuvant radiotherapy) …

Stereotactic ablative radiotherapy combined with immune checkpoint inhibitors reboots the immune response assisted by immunotherapy in metastatic lung cancer: a …

R Chicas-Sett, I Morales-Orue… - International journal of …, 2019 - mdpi.com
Background: Immune checkpoint inhibitors (ICI) have represented a revolution in the
treatment of non-small-cell lung cancer (NSCLC). To improve these results, combined …

[HTML][HTML] Combining stereotactic body radiation therapy with immunotherapy: current data and future directions

AJ Lin, M Roach, J Bradley… - Translational Lung Cancer …, 2019 - ncbi.nlm.nih.gov
Stereotactic body radiation therapy (SBRT) offers excellent local control of early-stage non-
small cell lung cancer (NSCLC), but there currently is a need for tolerable systemic therapy …

Immunoradiotherapy as an effective therapeutic strategy in lung cancer: From palliative care to curative intent

R Chicas-Sett, J Zafra-Martin, I Morales-Orue… - Cancers, 2020 - mdpi.com
Lung cancer is one of the main causes of cancer-related mortality worldwide. Over the years,
different therapeutic modalities have been adopted depending on tumor stage and patient …

[HTML][HTML] Immunotherapy and radiotherapy for metastatic cancers

A Bang, JD Schoenfeld - Annals of Palliative Medicine, 2019 - apm.amegroups.org
Immune checkpoint inhibitors have emerged as a breakthrough therapy in the treatment in
various metastatic cancers. In parallel, the role of radiotherapy in metastatic cancers has …

Immunotherapy-based combinations: an update

G Fucà, F de Braud, M Di Nicola - Current opinion in oncology, 2018 - journals.lww.com
Immunotherapy-based combinations: an update : Current Opinion in Oncology
Immunotherapy-based combinations: an update : Current Opinion in Oncology Log in or …

The combined use of SBRT and immunotherapy—a literature review

MJ Lubas, SS Kumar - Current Oncology Reports, 2020 - Springer
Abstract Purpose of Review The purpose of this paper is to review all recent and relevant
data regarding the combined use of immunotherapy (particularly immune checkpoint …

Novel drug treatments of progressive radioiodine-refractory differentiated thyroid cancer

SP Weitzman, SI Sherman - Endocrinology and Metabolism …, 2019 - endo.theclinics.com
Most patients treated for differentiated thyroid cancer (DTC) fare quite well. Data from the
Surveillance, Epidemiology, and End Results (SEER) program show that 98.1% of patients …

Systemic immunostimulatory effects of radiation therapy improves the outcomes of patients with advanced NSCLC receiving immunotherapy

MA D'Andrea, GK Reddy - American Journal of Clinical Oncology, 2020 - journals.lww.com
The understanding of localized radiation therapy's immunostimulatory properties combined
with its well-known effects on the cell cycle and insights into the immunomodulation …