Mucosal immunity: implications for vaccine development

J Holmgren, C Czerkinsky, N Lycke, AM Svennerholm - Immunobiology, 1992 - Elsevier
The mucosal surfaces in eg the gastrointestinal, respiratory and urogenital tracts represent a
very large exposure area to exogenous agents including microorganisms. Not surprising …

3 The humoral immune system in coeliac disease

M Mäki - Baillière's clinical gastroenterology, 1995 - Elsevier
IgA is transported into intestinal secretions to perform exclusion of luminal antigens. The
prerequisites are antigen sampling by the Peyer's patch M cells, antigen processing by …

Enhancement of the circulating antibody secreting cell response in human diarrhea by a human Lactobacillus strain

M Kaila, E Isolauri, ESA Soppi, E Virtanen, S Laine… - Pediatric …, 1992 - nature.com
Human Lactobacillus sp strain GG (Lactobacillus GG) administered during acute rotavirus
diarrhea has been shown to promote clinical recovery. To elucidate the immune …

Mode of delivery–effects on gut microbiota and humoral immunity

A Huurre, M Kalliomäki, S Rautava, M Rinne… - Neonatology, 2008 - karger.com
Background: The rate of caesarean deliveries has increased 10-fold worldwide during the
past decades. Objective: To evaluate differences in the establishment of gut microbiota in …

Lactobacillus casei strain GG reverses increased intestinal permeability induced by cow milk in suckling rats

E Isolauri, H Majamaa, T Arvola, I Rantala, E Virtanen… - Gastroenterology, 1993 - Elsevier
Background: Lactobacilli constitute a major part of the microflora throughout the
gastrointestinal tract. This study aimed to investigate the effect of lactobacilli on the gut …

Importance of intestinal colonisation in the maturation of humoral immunity in early infancy: a prospective follow up study of healthy infants aged 0–6 months

MM Grönlund, H Arvilommi, P Kero… - Archives of Disease in …, 2000 - fn.bmj.com
AIM To evaluate the role of intestinal microflora and early formula feeding in the maturation
of humoral immunity in healthy newborn infants. STUDY DESIGN Sixty four healthy infants …

Promotion of IgA Immune Response in Patients with Crohn's Disease by Oral Bacteriotherapy with Lactobacillus GG

M Malin, H Suomalainen, M Saxelin… - Annals of Nutrition and …, 1996 - karger.com
The effect of oral bacteriotherapy with human Lactobacillus casei strain GG (1010 colony-
forming units twice daily for 10 days) was investigated in Crohn's disease and in juvenile …

phoP/phoQ-Deleted Salmonella typhi (Ty800) Is a Safe and Immunogenic Single Dose Typhoid Fever Vaccine in Volunteers

EL Hohmann, CA Oletta, KP Killeen… - Journal of Infectious …, 1996 - academic.oup.com
The phoP/phoQ virulence regulatory genes of Salmonella typhi Ty2 were deleted, and the
resultant strain (Ty800) was tested as a live attenuated typhoid fever vaccine in human …

Effect of probiotics and breastfeeding on the bifidobacterium and lactobacillus/enterococcus microbiota and humoral immune responses

M Rinne, M Kalliomaki, H Arvilommi, S Salminen… - The Journal of …, 2005 - Elsevier
OBJECTIVE: To assess impact of probiotics and breastfeeding on gut microecology. STUDY
DESIGN: Mothers were randomized to receive placebo or Lactobacillus rhamnosus GG …

[HTML][HTML] Specific probiotics in enhancing maturation of IgA responses in formula-fed infants

S Rautava, H Arvilommi, E Isolauri - Pediatric research, 2006 - nature.com
The first months of life represent a critical period for the maturation of the infant's immune
system and, thus, a window of opportunity for measures to reduce the risk of disease. We …