Chemical signals, or neurotransmitters, represent the fundamental mode for intercellular
communication in the nervous system. 1 The classical model for neurotransmitter action …

Background: Fatty acid amide hydrolase (FAAH) is an integral membrane enzyme that
hydrolyzes the endocannabinoid anandamide and related amidated signaling lipids …

The integral membrane enzyme fatty acid amide hydrolase (FAAH) hydrolyzes the
endocannabinoid anandamide and related amidated signaling lipids. Genetic or …

Click chemistry is evolving as a powerful tool in biological applications because it allows the
sensitive and specific detection of compounds with alkyne or azido groups. Here we …

Fatty acid amide hydrolase (FAAH) overexpression induces several disorder symptoms in
nerve systems, and therefore long-term tracing of FAAH activity in vivo is of high importance …

We need better medicines to control acute and chronic pain. Fatty acid amide hydrolase
(FAAH) and soluble epoxide hydrolase (sEH) catalyze the deactivating hydrolysis of two …

Chlorpyrifos is an organophosphorus insecticide that elicits acute toxicity through inhibition
of acetylcholinesterase (AChE), leading to acetylcholine accumulation and prolonged …

Chlorpyrifos oxon (CPO) is the active metabolite of the organophosphorus pesticide,
chlorpyrifos. CPO is a potent inhibitor of acetylcholinesterase (AChE) and other serine …

Fatty acid amide hydrolase (FAAH) is responsible for regulating concentrations of the
endocannabinoid arachidonoyl ethanolamide. Multiple FAAH inhibitors have been …

Background Legislation at state, federal, and international levels is requiring rapid
evaluation of the toxicity of numerous chemicals. Whole-animal toxicologic studies cannot …