Polymeric nanoparticles for delivery of natural bioactive agents: recent advances and challenges

M Elmowafy, K Shalaby, MH Elkomy, OA Alsaidan… - Polymers, 2023 - mdpi.com
In the last few decades, several natural bioactive agents have been widely utilized in the
treatment and prevention of many diseases owing to their unique and versatile therapeutic …

Immune modulation by curcumin: The role of interleukin-10

H Mollazadeh, AFG Cicero, CN Blesso… - Critical reviews in …, 2019 - Taylor & Francis
Cytokines are small secreted proteins released by different types of cells with specific effects
on cellular signaling and communication via binding to their receptors on the cell surface. IL …

Oral administration of turmeric-derived exosome-like nanovesicles with anti-inflammatory and pro-resolving bioactions for murine colitis therapy

C Liu, X Yan, Y Zhang, M Yang, Y Ma, Y Zhang… - Journal of …, 2022 - Springer
Background Ulcerative colitis (UC) is an inflammatory bowel disease (IBD) characterized by
diffuse inflammation of the colonic mucosa and a relapsing and remitting course. The current …

Shaoyao decoction attenuates DSS-induced ulcerative colitis, macrophage and NLRP3 inflammasome activation through the MKP1/NF-κB pathway

Y Wei, Y Fan, Y Ga, Y Zhang, J Han, Z Hao - Phytomedicine, 2021 - Elsevier
Background Shaoyao decoction (SYD), a traditional Chinese medicine prescription that
originated in the Jin-Yuan Dynasty, has shown effects in treating ulcerative colitis. However …

Herbs and spices-biomarkers of intake based on human intervention studies–a systematic review

R Vázquez-Fresno, ARR Rosana, T Sajed… - Genes & nutrition, 2019 - Springer
Culinary herbs and spices have been used as both food flavoring and food preservative
agents for centuries. Moreover, due to their known and presumptive health benefits, herbs …

Curcumin improves intestinal barrier function: modulation of intracellular signaling, and organization of tight junctions

J Wang, SS Ghosh, S Ghosh - American Journal of …, 2017 - journals.physiology.org
Association between circulating lipopolysaccharide (LPS) and metabolic diseases (such as
type 2 diabetes and atherosclerosis) has shifted the focus from high-fat high-cholesterol …

The effect of curcumin supplementation on clinical outcomes and inflammatory markers in patients with ulcerative colitis

N Sadeghi, A Mansoori, A Shayesteh… - Phytotherapy …, 2020 - Wiley Online Library
Background and aims Curcumin has anti‐inflammatory properties. The aim of this study was
to evaluate the effect of curcumin on improvement of the disease activity in ulcerative colitis …

Curcumin and its modified formulations on inflammatory bowel disease (IBD): The story so far and future outlook

A Karthikeyan, KN Young, M Moniruzzaman… - Pharmaceutics, 2021 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic relapsing and remitting inflammatory disorder
of the small intestine and colon. IBD includes ulcerative colitis (UC) and Crohn's disease …

[HTML][HTML] Principles of pharmacological research of nutraceuticals

R Andrew, AA Izzo - British Journal of Pharmacology, 2017 - ncbi.nlm.nih.gov
The term 'nutraceutical', a hybrid term introduced in 1989 to designate the link between
'nutrition'and 'pharmaceutical agents', has actually no universally accepted definition …

[HTML][HTML] Regulative effects of curcumin spice administration on gut microbiota and its pharmacological implications

L Shen, L Liu, HF Ji - Food & nutrition research, 2017 - Taylor & Francis
Curcumin, the major active component of turmeric (Curcuma longa), is widely used as a
spice and food-coloring agent, and also exhibits multiple biological activities. However, as …