Glioblastoma multiforme (GBM) is commonly known as the most aggressive primary CNS
tumor in adults. The mean survival of it is 14 to 15 months, following the standard therapy …

Systemic chemotherapy given at maximum tolerated doses (MTD) has been the mainstay of
cancer treatment for more than half a century. In some chemosensitive diseases such as …

The dynamic cancer ecosystem, with its rich temporal and spatial diversity in environmental
conditions and heritable cell phenotypes, is remarkably robust to therapeutic perturbations …

Despite continuous deployment of new treatment strategies and agents over many decades,
most disseminated cancers remain fatal. Cancer cells, through their access to the vast …

Importance Induction or adjuvant chemotherapy with concurrent chemoradiotherapy (CCRT)
are first-line treatment options for treatment of locoregionally advanced nasopharyngeal …

Nasopharyngeal carcinoma is a rare disease in Western countries. Nevertheless, its
incidence in China, Singapore, and other Eastern countries reaches 20 cases per 100,000 …

Viral malignancies represent a distinct entity among cancers. Oncoviruses like the Human
Papilloma Virus (HPV) and the Epstein Barr Virus (EBV) are highly potent inducers of …

In this study, we investigated the immune-modulating effects of a novel metronomic
chemotherapy (MCT) featuring combined oral oxaliplatin (OXA) and pemetrexed (PMX) for …

Background The role of capecitabine in neoadjuvant and adjuvant chemotherapy for early-
stage triple-negative breast cancer (TNBC) is highly controversial. Our meta-analysis was …

Hepatocellular carcinoma (HCC) is a cancer with a high mortality rate due to the fact that the
diagnosis usually occurs at anadvanced stage. Even in case of curative surgical treatment …