Fibrin mechanical properties and their structural origins

RI Litvinov, JW Weisel - Matrix Biology, 2017 - Elsevier
Fibrin is a protein polymer that is essential for hemostasis and thrombosis, wound healing,
and several other biological functions and pathological conditions that involve extracellular …

Constrained mixture models of soft tissue growth and remodeling–twenty years after

JD Humphrey - Journal of Elasticity, 2021 - Springer
Soft biological tissues compromise diverse cell types and extracellular matrix constituents,
each of which can possess individual natural configurations, material properties, and rates …

Homogenized constrained mixture models for anisotropic volumetric growth and remodeling

FA Bräu, A Seitz, RC Aydin, CJ Cyron - Biomechanics and modeling in …, 2017 - Springer
Constrained mixture models for soft tissue growth and remodeling have attracted increasing
attention over the last decade. They can capture the effects of the simultaneous presence of …

Deep learning on multiphysical features and hemodynamic modeling for abdominal aortic aneurysm growth prediction

S Kim, Z Jiang, BA Zambrano, Y Jang… - … on Medical Imaging, 2022 - ieeexplore.ieee.org
Prediction of abdominal aortic aneurysm (AAA) growth is of essential importance for the
early treatment and surgical intervention of AAA. Capturing key features of vascular growth …

Model predictions of deformation, embolization and permeability of partially obstructive blood clots under variable shear flow

S Xu, Z Xu, OV Kim, RI Litvinov… - Journal of the …, 2017 - royalsocietypublishing.org
Thromboembolism, one of the leading causes of morbidity and mortality worldwide, is
characterized by formation of obstructive intravascular clots (thrombi) and their mechanical …

Biomechanical consequences of compromised elastic fiber integrity and matrix cross-linking on abdominal aortic aneurysmal enlargement

D Weiss, M Latorre, BV Rego, C Cavinato, BJ Tanski… - Acta biomaterialia, 2021 - Elsevier
Abdominal aortic aneurysms (AAAs) are characterized histopathologically by compromised
elastic fiber integrity, lost smooth muscle cells or their function, and remodeled collagen. We …

A finite element implementation of a growth and remodeling model for soft biological tissues: Verification and application to abdominal aortic aneurysms

N Horvat, L Virag, GA Holzapfel, J Sorić… - Computer methods in …, 2019 - Elsevier
The general framework for growth and remodeling (G&R) of soft biological tissues shows a
great potential for expanding our current understanding of biochemical and biomechanical …

Imaging and biophysical modelling of thrombogenic mechanisms in atrial fibrillation and stroke

A Qureshi, GYH Lip, DA Nordsletten… - Frontiers in …, 2023 - frontiersin.org
Atrial fibrillation (AF) underlies almost one third of all ischaemic strokes, with the left atrial
appendage (LAA) identified as the primary thromboembolic source. Current stroke risk …

Prediction of wall stress and oxygen flow in patient-specific abdominal aortic aneurysms: the role of intraluminal thrombus

A Throop, M Bukac, R Zakerzadeh - Biomechanics and modeling in …, 2022 - Springer
In this study, the biomechanical role of intraluminal thrombus (ILT) in an abdominal aortic
aneurysm (AAA) is investigated. The implications of ILT in AAA are controversial in literature …

Global sensitivity analysis of a homogenized constrained mixture model of arterial growth and remodeling

S Brandstaeter, SL Fuchs, J Biehler, RC Aydin… - Journal of elasticity, 2021 - Springer
Growth and remodeling in arterial tissue have attracted considerable attention over the last
decade. Mathematical models have been proposed, and computational studies with these …