Congestion in heart failure: a circulating biomarker‐based perspective. A review from the Biomarkers Working Group of the Heart Failure Association, European …

J Núñez, R de la Espriella, P Rossignol… - European Journal of …, 2022 - Wiley Online Library
Congestion is a cardinal sign of heart failure (HF). In the past, it was seen as a
homogeneous epiphenomenon that identified patients with advanced HF. However, current …

Natriuretic peptides: role in the diagnosis and management of heart failure: a scientific statement from the Heart Failure Association of the European Society of …

H Tsutsui, NM Albert, AJS Coats, SD Anker… - Journal of Cardiac …, 2023 - Elsevier
Natriuretic peptides, brain (B-type) natriuretic peptide (BNP) and N-terminal prohormone of
brain natriuretic peptide (NT-proBNP) are globally and most often used for the diagnosis of …

Antigen carbohydrate 125 as a biomarker in heart failure: a narrative review

J Núñez, R de la Espriella, G Miñana… - European journal of …, 2021 - Wiley Online Library
Congestion explains many of the signs and symptoms of acute heart failure (AHF) and
disease progression. However, accurate quantification of congestion is challenging in daily …

Tricuspid valve academic research consortium definitions for tricuspid regurgitation and trial endpoints

RT Hahn, MK Lawlor, CJ Davidson… - European heart …, 2023 - academic.oup.com
Interest in the pathophysiology, etiology, management, and outcomes of patients with
tricuspid regurgitation (TR) has grown in the wake of multiple natural history studies showing …

A new classification of cardio-oncology syndromes

RA de Boer, JP Aboumsallem, V Bracun, D Leedy… - Cardio-oncology, 2021 - Springer
Increasing evidence suggests a multifaceted relationship exists between cancer and
cardiovascular disease (CVD). Here, we introduce a 5-tier classification system to categorize …

Epidemiology, pathophysiology, diagnosis and management of chronic right‐sided heart failure and tricuspid regurgitation. A clinical consensus statement of the Heart …

M Adamo, O Chioncel, M Pagnesi… - European journal of …, 2024 - Wiley Online Library
Right‐sided heart failure and tricuspid regurgitation are common and strongly associated
with poor quality of life and an increased risk of heart failure hospitalizations and death …

Association of carbohydrate antigen 125 on the response to dapagliflozin in patients with heart failure

KF Docherty, K McDowell, P Welsh, J Osmanska… - Journal of the American …, 2023 - jacc.org
Background Elevated circulating carbohydrate antigen 125 (CA125) is a marker of
congestion and a predictor of outcomes in acute heart failure (HF). Less is known about …

Carbohydrate antigen 125 in congestive heart failure: ready for clinical application?

R Feng, Z Zhang, Q Fan - Frontiers in Oncology, 2023 - frontiersin.org
Congestion is the permanent mechanism driving disease progression in patients with acute
heart failure (AHF) and also is an important treatment target. However, distinguishing …

Prognostic value of NT-proBNP and CA125 across glomerular filtration rate categories in acute heart failure

R de la Espriella, A Bayes-Genis, P Llacer… - European journal of …, 2022 - Elsevier
Background This study aimed to evaluate whether glomerular filtration rate (eGFR) during
admission modifies the predictive value of plasma amino-terminal pro-brain natriuretic …

Carbohydrate antigen 125 concentrations across the ejection fraction spectrum in chronic heart failure: The EMPEROR programme

JP Ferreira, M Packer, N Sattar, J Butler… - European Journal of …, 2024 - Wiley Online Library
Aim Vascular congestion may lead to an increase of carbohydrate antigen 125 (CA‐125).
The role of CA‐125 as a biomarker of congestion or for prognosis across the full ejection …