Diabetes prevalence continues to climb with the aging population. Type 2 diabetes (T2D),
which constitutes most cases, is metabolically acquired. Diabetic peripheral neuropathy …

Vitamin B12 (B12) is an essential cofactor of two important biochemical pathways, the
degradation of methylmalonic acid and the synthesis of methionine from homocysteine …

Diabetic neuropathy (DN), the most common chronic and progressive complication of
diabetes mellitus (DM), strongly affects patients' quality of life. DN could be present as …

Metabolic diseases and their complications impose health and economic burdens
worldwide. Evidence from past experimental studies and clinical trials suggests our body …

Diabetic peripheral neuropathy (DPN) is the most common complication of diabetes mellitus
(DM) and the dysfunction of Schwann cells plays an important role in the pathogenesis of …

As a common complication of diabetes, the pathogenesis of diabetic peripheral neuropathy
(DPN) is closely related to high glucose but has not been clarified. Exosomes can mediate …

Genome-wide studies provide considerable insights into the genetic background of animals;
however, the inheritance of several heritable factors cannot be elucidated. Epigenetics …

There has recently been a growing interest in examining the role of epigenetic modifications,
such as DNA methylation, in the etiology of type 1 diabetes (T1D). This study aimed to …

Diabetic kidney disease (DKD) and diabetic peripheral neuropathy (DPN) are two common
diabetic complications. However, their pathogenesis remains elusive and current therapies …

Mechanical allodynia (MA) is the main reason that patients with diabetic peripheral
neuropathy (DPN) seek medical advice. It severely debilitates the quality of life. Investigating …