Environmental hotspots for antibiotic resistance genes

S Kunhikannan, CJ Thomas, AE Franks… - …, 2021 - Wiley Online Library
Bacterial resistance toward broad‐spectrum antibiotics has become a major concern in
recent years. The threat posed by the infectious bacteria and the pace with which resistance …

Antimicrobial resistance in developing countries. Part I: recent trends and current status

IN Okeke, R Laxminarayan, ZA Bhutta… - The Lancet infectious …, 2005 - thelancet.com
The global problem of antimicrobial resistance is particularly pressing in developing
countries, where the infectious disease burden is high and cost constraints prevent the …

High prevalence of antibiotic resistance in commensal Escherichia coli from healthy human sources in community settings

E Nji, J Kazibwe, T Hambridge, CA Joko, AA Larbi… - Scientific reports, 2021 - nature.com
Antibiotic resistance is a global health crisis that requires urgent action to stop its spread. To
counteract the spread of antibiotic resistance, we must improve our understanding of the …

The human microbiome as a reservoir of antimicrobial resistance

J Penders, EE Stobberingh, PHM Savelkoul… - Frontiers in …, 2013 - frontiersin.org
The gut microbiota is amongst the most densely populated microbial ecosystem on earth.
While the microbiome exerts numerous health beneficial functions, the high density of micro …

Commensal Escherichia coli of healthy humans: a reservoir for antibiotic-resistance determinants

JK Bailey, JL Pinyon, S Anantham… - Journal of medical …, 2010 - microbiologyresearch.org
This study examined in detail the population structure of Escherichia coli from healthy adults
with respect to the prevalence of antibiotic resistance and specific resistance determinants …

[HTML][HTML] Growing problem of multidrug-resistant enteric pathogens in Africa

IN Okeke, OA Aboderin, DK Byarugaba… - Emerging infectious …, 2007 - ncbi.nlm.nih.gov
Control of fecal–orally transmitted pathogens is inadequate in many developing countries, in
particular, in sub-Saharan Africa. Acquired resistance to antimicrobial drugs is becoming …

Escherichia coli β-Lactamases: What Really Matters

P Bajaj, NS Singh, JS Virdi - Frontiers in microbiology, 2016 - frontiersin.org
Escherichia coli strains belonging to diverse pathotypes have increasingly been recognized
as a major public health concern. The β-lactam antibiotics have been used successfully to …

Detection and characterization of ESBL-producing Enterobacteriaceae from the gut of subsistence farmers, their livestock, and the surrounding environment in rural …

SH Subramanya, I Bairy, Y Metok, BP Baral… - Scientific reports, 2021 - nature.com
The increasing trend of gut colonization by extended-spectrum β-lactamase (ESBL)
producing Enterobacterales has been observed in conventional farm animals and their …

[HTML][HTML] Multidrug-resistant commensal Escherichia coli in children, Peru and Bolivia

A Bartoloni, L Pallecchi, M Benedetti… - Emerging infectious …, 2006 - ncbi.nlm.nih.gov
Using a rapid screening method, we investigated the prevalence of fecal carriage of
antimicrobial drug–resistant Escherichia coli in 3,174 healthy children from 4 urban settings …

Antimicrobial susceptibility profiles of Escherichia coli and Klebsiella pneumoniae isolated from outpatients in urban and rural districts of Uganda

CF Najjuka, DP Kateete, HM Kajumbula, ML Joloba… - BMC research …, 2016 - Springer
Background Antimicrobial resistance is a global public health concern contributing to
increased morbidity and mortality particularly in low-income countries. Studies on …