DNA is fundamentally important for all cellular organisms due to its role as a store of
hereditary genetic information. The precise and accurate regulation of gene transcription …

Fusobacterium nucleatum, long known as a constituent of the oral microflora, has recently
garnered renewed attention for its association with several different human cancers. The …

As one of the most common bacterial pathogens causing nosocomial infections,
Pseudomonas aeruginosa is highly adaptable to survive under various conditions. Here, we …

Global RNA profiling studies in bacteria have predicted the existence of many of small
noncoding RNAs (sRNAs) that are processed off mRNA 3′ ends to regulate other mRNAs …

Pseudomonas aeruginosa is an opportunistic pathogen that causes difficult-to-treat
infections. Two well-studied divergent P. aeruginosa strain types, PAO1 and PA14, have …

Abstract The Serine Protease Inhibitor (serpin) protein has been suggested to play a key
role in the interaction of bifidobacteria with the host. By inhibiting intestinal serine proteases …

Bacterial genomes are now recognized as interacting intimately with cellular processes.
Uncovering organizational mechanisms of bacterial genomes has been a primary focus of …

Gene arrays and operons that encode functionally linked proteins form the most basic unit of
transcriptional regulation in bacteria. Rules that govern the order and orientation of genes in …

Operon prediction in prokaryotes is critical not only for understanding the regulation of
endogenous gene expression, but also for exogenous targeting of genes using newly …

Transcriptional-translational coupling is accepted to be a fundamental mechanism of gene
expression in prokaryotes and therefore has been analyzed in detail. However, the …