Aerosol drug delivery: developments in device design and clinical use

MB Dolovich, R Dhand - The Lancet, 2011 - thelancet.com
Aerosolised drugs are prescribed for use in a range of inhaler devices and systems.
Delivering drugs by inhalation requires a formulation that can be successfully aerosolised …

Dry powder inhalers (DPIs)—a review of device reliability and innovation

N Islam, E Gladki - International journal of pharmaceutics, 2008 - Elsevier
A wide range of dry powder inhaler (DPI) devices are currently available on the market to
deliver drugs into lungs with a view to maximise drug delivery with low variability. DPIs also …

[PDF][PDF] Jet, Ultrasonic, and Mesh Nebulizers: An Evaluation of Nebulizers for Better Clinical Outcomes.

A Arı - Eurasian Journal of Pulmonology, 2014 - jag.journalagent.com
For over a century, nebulizers have been commonly used to deliver aerosolized medications
in the treatment of patients with pulmonary diseases. They are the aerosol device of choice …

The influence of fluid physicochemical properties on vibrating-mesh nebulization

T Ghazanfari, AMA Elhissi, Z Ding… - International journal of …, 2007 - Elsevier
In this study, the effect of fluid physicochemical properties and the vibrating-mesh
mechanism on the aerosols generated from vibrating-mesh nebulizers have been evaluated …

The function and performance of aqueous aerosol devices for inhalation therapy

TC Carvalho, JT McConville - Journal of Pharmacy and …, 2016 - academic.oup.com
Objectives In this review paper, we explore the interaction between the functioning
mechanism of different nebulizers and the physicochemical properties of the formulations for …

Nebulization as a delivery method for mAbs in respiratory diseases

R Respaud, L Vecellio, P Diot… - Expert opinion on drug …, 2015 - Taylor & Francis
Introduction: The pulmonary route is not invasive and can be used to target drugs directly to
the lungs, limiting the exposure of secondary organs. It is, thus, an attractive alternative to …

Advanced nebulizer designs employing vibrating mesh/aperture plate technologies for aerosol generation

JC Waldrep, R Dhand - Current Drug Delivery, 2008 - ingentaconnect.com
Recent technological advances and improved nebulizer designs have overcome many
limitations of jet nebulizers. Newer devices employ a vibrating mesh or aperture plate …

Preservation of DNA

TJ Anchordoquy, MC Molina - Cell Preservation Technology, 2007 - liebertpub.com
The preservation of DNA is of wide interest to scientists in disparate fields from biorepository
management to pharmaceutical sciences. Although the term “preservation” is used by all …

Effective pulmonary delivery of an aerosolized plasmid DNA vaccine via surface acoustic wave nebulization

AE Rajapaksa, JJ Ho, A Qi, R Bischof, TH Nguyen… - Respiratory …, 2014 - Springer
Background Pulmonary-delivered gene therapy promises to mitigate vaccine safety issues
and reduce the need for needles and skilled personnel to use them. While plasmid DNA …

Current therapies and technological advances in aqueous aerosol drug delivery

AB Watts, JT McConville… - Drug development and …, 2008 - Taylor & Francis
Recent advances in aerosolization technology have led to renewed interest in pulmonary
delivery of a variety of drugs. Pressurized metered dose inhalers (pMDIs) and dry powder …