Nucleoli are the site of ribosomal RNA production and subunit assembly. In contrast to active
nucleoli in somatic cells, where three basic sub-compartments can be observed, mammalian …

In nearly all somatic cells, the ribosome biosynthesis is a key activity. The same is true also
for mammalian oocytes and early embryos. This activity is intimately linked to the most …

Mammalian oocytes/zygotes contain atypical nucleoli that are composed exclusively of a
dense fibrillar material. It has been commonly accepted that these nucleoli serve as a …

It is now approximately 25 years since the sheep Dolly, the first cloned mammal where the
somatic cell nucleus from an adult donor was used for transfer, was born. So far, somatic cell …

Sequence differences are considered to be the basic cause of developmental failure in
interspecies embryos when more distant species are combined. However, other …

The nucleolus is an important nucleus sub-organelle found in almost all eukaryotic cells. On
the one hand, it is known as a differentiated active site of ribosome biogenesis in somatic …

The nucleolus is the cell organelle responsible for ribosome synthesis and, hence, for
protein synthesis. In the mammalian oocyte, the nucleolus compacts into a dense sphere …