Computational microstructure characterization and reconstruction: Review of the state-of-the-art techniques

R Bostanabad, Y Zhang, X Li, T Kearney… - Progress in Materials …, 2018 - Elsevier
Building sensible processing-structure-property (PSP) links to gain fundamental insights and
understanding of materials behavior has been the focus of many works in computational …

Review of statistical model calibration and validation—from the perspective of uncertainty structures

G Lee, W Kim, H Oh, BD Youn, NH Kim - Structural and Multidisciplinary …, 2019 - Springer
Computer-aided engineering (CAE) is now an essential instrument that aids in engineering
decision-making. Statistical model calibration and validation has recently drawn great …

Soft discoidal polymeric nanoconstructs resist macrophage uptake and enhance vascular targeting in tumors

J Key, AL Palange, F Gentile, S Aryal, C Stigliano… - ACS …, 2015 - ACS Publications
Most nanoparticles for biomedical applications originate from the self-assembling of
individual constituents through molecular interactions and possess limited geometry control …

Hybrid modeling frameworks of tumor development and treatment

IM Chamseddine, KA Rejniak - Wiley Interdisciplinary Reviews …, 2020 - Wiley Online Library
Tumors are complex multicellular heterogeneous systems comprised of components that
interact with and modify one another. Tumor development depends on multiple factors …

Cell and nanoparticle transport in tumour microvasculature: the role of size, shape and surface functionality of nanoparticles

Y Li, Y Lian, LT Zhang, SM Aldousari… - Interface …, 2016 - royalsocietypublishing.org
Through nanomedicine, game-changing methods are emerging to deliver drug molecules
directly to diseased areas. One of the most promising of these is the targeted delivery of …

Deep-learning-based porous media microstructure quantitative characterization and reconstruction method

Y Huang, Z Xiang, M Qian - Physical Review E, 2022 - APS
Microstructure characterization and reconstruction (MCR) is one of the most important
components of discovering processing-structure-property relations of porous media …

[HTML][HTML] Blood cells as supercarrier systems for advanced drug delivery

S Wang, K Han, S Ma, X Qi, L Guo, X Li - Medicine in Drug Discovery, 2022 - Elsevier
In recent years, drug delivery has emerged as a more and more popular drug administration
means for the improvement of pharmacokinetics, minimization of side effects, and …

Multiscale modeling and uncertainty quantification in nanoparticle-mediated drug/gene delivery

Y Li, W Stroberg, TR Lee, HS Kim, H Man, D Ho… - Computational …, 2014 - Springer
Abstract Nanoparticle (NP)-mediated drug/gene delivery involves phenomena at broad
range spatial and temporal scales. The interplay between these phenomena makes the NP …

Multiscale modeling and simulation of nano‐carriers delivery through biological barriers—a review

X Shi, F Tian - Advanced Theory and Simulations, 2019 - Wiley Online Library
The past several decades have witnessed the explosion of nanomedicine for cancer
therapy, where notable research efforts have been made in synthesizing and delivering …

Particle morphology: an important factor affecting drug delivery by nanocarriers into solid tumors

Z Wang, Z Wu, J Liu, W Zhang - Expert opinion on drug delivery, 2018 - Taylor & Francis
Introduction: Efficient delivery of drugs by nanoparticles deep into solid tumors is the
precondition of valid cancer therapy. Despite profound understanding of the delivery of …