Transcriptome studies reveal pervasive transcription of complex genomes, such as those of
mammals. Despite popular arguments for functionality of most, if not all, of these transcripts …

CRISPR-Cas, the bacterial and archaeal adaptive immunity systems, encompass a complex
machinery that integrates fragments of foreign nucleic acids, mostly from mobile genetic …

Pentatricopeptide repeat (PPR) proteins constitute one of the largest protein families in land
plants, with more than 400 members in most species. Over the past decade, much has been …

Plant organellar RNA metabolism is run by a multitude of nucleus-encoded RNA-binding
proteins (RBPs) that control RNA stability, processing, and degradation. In chloroplasts and …

Most proteins assemble into multisubunit complexes. The persistence of these complexes
across evolutionary time is usually explained as the result of natural selection for functional …

Mitochondria have specialized ribosomes that have diverged from their bacterial and
cytoplasmic counterparts. We have solved the structure of the yeast mitoribosomal large …

Mitochondrial and plastid genomes show a wide array of architectures, varying immensely in
size, structure, and content. Some organelle DNAs have even developed elaborate …

Do data from the Encyclopedia Of DNA Elements (ENCODE) project render the notion of
junk DNA obsolete? Here, I review older arguments for junk grounded in the C-value …

The Logic of Chance offers a reappraisal and a new synthesis of theories, concepts, and
hypotheses on the key aspects of the evolution of life on earth in light of comparative …

The study of reproductive isolation and species barriers frequently focuses on mitochondrial
genomes and has produced two alternative and almost diametrically opposed narratives. On …