Imidazole ring is an important five‐membered aromatic heterocycle widely present in natural
products and synthetic molecules. The unique structural feature of imidazole ring with …

Fungal infections impact the lives of at least 12 million people every year, killing over 1.5
million. Wide-spread use of fungicides and prophylactic antifungal therapy have driven …

The reaction of 3-chlorobenzo [b] thiophene-2-carbohydrazide with 4-(diethylamino)
salicylaldehyde gave the new ligand; 3-chloro-N'-(4-(diethylamino)-2-hydroxybenzylidene) …

Summary Abstract Sertaconazole (Dermofix®, Ertaczo™, Ginedermofix®, Monazol,
Mykosert® or Zalain®), an imidazole antifungal agent, inhibits the synthesis of ergosterol, an …

This review provides a historical overview of the analog based drug discovery of miconazole
and its congeners, and is focused on marketed azole antifungals bearing the generic suffix …

Dermatophytes are amongst the most common causative agents of fungal infections
worldwide and widespread in the developing countries. Various studies have found the …

Background: Sertaconazole is a new, broad spectrum, fungicidal and fungistatic imidazole
with added antipruritic and anti-inflammatory activity that would provide greater symptomatic …

Background Facial seborrheic dermatitis (SD), a chronic inflammatory skin condition, can
impact quality of life, and relapses can be frequent. Three broad categories of agents are …

Imidazole and its derivatives are one of the most important and widely used heterocycles in
medicinal chemistry, natural products, and synthetic chemicals. Because of the imidazole …

A microemulsion (ME) based hydrogel had studied as a topical delivery of sertaconazole
(STZL) for effective eradication of cutaneous fungal infection. The existence of …