Cardiac autonomic neuropathy in obesity, the metabolic syndrome and prediabetes: a narrative review

SM Williams, A Eleftheriadou, U Alam, DJ Cuthbertson… - Diabetes Therapy, 2019 - Springer
Cardiac autonomic neuropathy (CAN) is a major complication of type 1 and type 2 diabetes
mellitus (T1DM and T2DM). The increased morbidity, cardiovascular and all-cause mortality …

Sympathetic system activity in obesity and metabolic syndrome

N Tentolouris, S Liatis… - Annals of the New York …, 2006 - Wiley Online Library
Obesity is a very common disease worldwide, resulting from a disturbance in the energy
balance. The metabolic syndrome is also a cluster of abnormalities with basic characteristics …

On the origins of sleep disordered breathing, cardiorespiratory and metabolic dysfunction: which came first, the chicken or the egg?

SV Conde, VY Polotsky, V Joseph… - The Journal of …, 2023 - Wiley Online Library
Sleep disordered breathing (SDB) is a complex, sex specific and highly heterogeneous
group of respiratory disorders. Nevertheless, sleep fragmentation and repeated fluctuations …

Obstructive sleep apnea

LV Pham, J Jun, VY Polotsky - Handbook of clinical neurology, 2022 - Elsevier
Obstructive sleep apnea (OSA) is a disease that results from loss of upper airway muscle
tone leading to upper airway collapse during sleep in anatomically susceptible persons …

Baroreflex control of heart rate during sleep in severe obstructive sleep apnoea: effects of acute CPAP

MR Bonsignore, G Parati, G Insalaco… - European …, 2006 - Eur Respiratory Soc
Baroreflex control of heart rate during sleep (baroreflex sensitivity; BRS) has been shown to
be depressed in obstructive sleep apnoea (OSA), and improved after treatment with …

Nocturnal autonomic function in preschool children with sleep-disordered breathing

LC Nisbet, SR Yiallourou, GM Nixon, SN Biggs… - Sleep Medicine, 2013 - Elsevier
Background Obstructive sleep apnea (OSA) is associated with autonomic dysfunction in
adults and school-aged children; however, this association has not been investigated in …

Determinants of heart rate variability in obstructive sleep apnea syndrome during wakefulness and sleep

JA Jo, A Blasi, E Valladares, R Juarez… - American Journal …, 2005 - journals.physiology.org
Heart rate variability (HRV) is mediated by at least three primary mechanisms: 1) vagal
feedback from pulmonary stretch receptors (PSR), 2) central medullary coupling between …

Predictors of decreased spontaneous baroreflex sensitivity in obstructive sleep apnea syndrome

S Ryan, S Ward, C Heneghan, WT McNicholas - Chest, 2007 - Elsevier
Background The impact of obstructive sleep apnea syndrome (OSAS) on the arterial
baroreflex, and its significance, is still under debate. We investigated the baroreflex …

The link between cardiac autonomic activity and sleep delta power is altered in men with sleep apnea-hypopnea syndrome

F Jurysta, JP Lanquart… - American Journal …, 2006 - journals.physiology.org
We hypothesize that sleep apnea-hypopnea alters interaction between cardiac vagal
modulation and sleep delta EEG. Sleep apnea-hypopnea syndrome (SAHS) is related to …

Impaired blood pressure control in children with obstructive sleep apnea

LM Walter, SR Yiallourou, A Vlahandonis, SA Sands… - Sleep Medicine, 2013 - Elsevier
Background Obstructive sleep apnea (OSA) in adults has been associated with
hypertension, low baroreflex sensitivity (BRS), a delayed heart rate response to changing …