Recent strategies to develop innovative photosensitizers for enhanced photodynamic therapy

TC Pham, VN Nguyen, Y Choi, S Lee, J Yoon - Chemical reviews, 2021 - ACS Publications
This review presents a robust strategy to design photosensitizers (PSs) for various species.
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …

Heavy-atom-free photosensitizers: from molecular design to applications in the photodynamic therapy of cancer

VN Nguyen, Y Yan, J Zhao, J Yoon - Accounts of chemical …, 2020 - ACS Publications
Conspectus Photodynamic therapy (PDT) is a clinically approved therapeutic modality that
has shown great potential for the treatment of cancers owing to its excellent spatiotemporal …

Cancer therapeutics based on diverse energy sources

S Son, J Kim, J Kim, B Kim, J Lee, Y Kim, M Li… - Chemical Society …, 2022 - pubs.rsc.org
Light-based phototherapy has been developed for cancer treatment owing to its non-
invasiveness and spatiotemporal control. Despite the unique merits of phototherapy, one …

ER-targeting cyanine dye as an NIR photoinducer to efficiently trigger photoimmunogenic cancer cell death

H Ma, Y Lu, Z Huang, S Long, J Cao… - Journal of the …, 2022 - ACS Publications
Endoplasmic reticulum (ER) stress, caused by overproduction of reactive oxygen species
(ROS), has been shown to be responsible for immunogenic cell death (ICD). Seeking ROS …

Long-wavelength photoconvertible dimeric BODIPYs for super-resolution single-molecule localization imaging in near-infrared emission

Q Gong, X Zhang, W Li, X Guo, Q Wu… - Journal of the …, 2022 - ACS Publications
Sulfoxide-bridged dimeric BODIPYs were developed as a new class of long-wavelength
photoconvertible fluorophores. Upon visible-light irradiation, a sulfoxide moiety was …

Recent development of heavy-atom-free triplet photosensitizers: molecular structure design, photophysics and application

X Zhang, Z Wang, Y Hou, Y Yan, J Zhao… - Journal of Materials …, 2021 - pubs.rsc.org
Triplet photosensitizers (PSs) have attracted much attention in recent years, due to the
significance of these kinds of compounds in fundamental photochemistry studies and …

Comprehensive thione-derived perylene diimides and their bio-conjugation for simultaneous imaging, tracking, and targeted photodynamic therapy

YL Lee, YT Chou, BK Su, C Wu, CH Wang… - Journal of the …, 2022 - ACS Publications
In this study, the chromophore 3, 4, 9, 10-perylenetetracarboxylic diimide (PDI) is anchored
with phenyl substituents at the imide N site, followed by thionation, yielding a series of thione …

Advancing biomedical applications via manipulating intersystem crossing

W Li, J Zhang, Z Gao, J Qi, D Ding - Coordination Chemistry Reviews, 2022 - Elsevier
Precision diagnosis and treatment have received increasing attention for modern medicine,
and the optical imaging and therapeutic techniques (eg, fluorescence imaging …

Trojan Horse‐Like Nano‐AIE Aggregates Based on Homologous Targeting Strategy and Their Photodynamic Therapy in Anticancer Application

Y Li, R Zhang, Q Wan, R Hu, Y Ma, Z Wang… - Advanced …, 2021 - Wiley Online Library
Photodynamic therapy (PDT) has become a promising candidate for cancer theranostics;
however, traditional photosensitizers (PSs) usually exhibit weak fluorescence and poor …

[HTML][HTML] Thionated organic compounds as emerging heavy-atom-free photodynamic therapy agents

LA Ortiz-Rodríguez, CE Crespo-Hernández - Chemical Science, 2020 - pubs.rsc.org
This minireview focuses on recent progress in developing heavy-atom-free photosensitizers
based on the thionation of nucleic acid derivatives and other biocompatible organic …