A systems‐level study reveals host‐targeted repurposable drugs against SARS‐CoV‐2 infection
Understanding the mechanism of SARS‐CoV‐2 infection and identifying potential
therapeutics are global imperatives. Using a quantitative systems pharmacology approach …
therapeutics are global imperatives. Using a quantitative systems pharmacology approach …
DrugWAS: drug‐wide association studies for COVID‐19 drug repurposing
This study aimed to systematically investigate if any of the available drugs in the electronic
health record (EHR) can be repurposed as potential treatment for coronavirus disease 2019 …
health record (EHR) can be repurposed as potential treatment for coronavirus disease 2019 …
Computational drug repurposing against SARS-CoV-2 reveals plasma membrane cholesterol depletion as key factor of antiviral drug activity
Comparing SARS-CoV-2 infection-induced gene expression signatures to drug treatment-
induced gene expression signatures is a promising bioinformatic tool to repurpose existing …
induced gene expression signatures is a promising bioinformatic tool to repurpose existing …
Fármacos potencialmente útiles en el tratamiento de la COVID-19 en Atención Primaria
L García-Matarín, S Velilla-Zancada… - Medicina de Familia …, 2022 - Elsevier
Las consecuencias de la pandemia por el SARS-CoV-2 han desbordado cualquier
previsión realizada. Hoy sabemos que el nivel de gravedad de la infección en sus fases …
previsión realizada. Hoy sabemos que el nivel de gravedad de la infección en sus fases …
The multidirectional effect of azelastine hydrochloride on cervical cancer cells
E Trybus, T Król, W Trybus - International Journal of Molecular Sciences, 2022 - mdpi.com
A major cause of cancer cell resistance to chemotherapeutics is the blocking of apoptosis
and induction of autophagy in the context of cell adaptation and survival. Therefore, new …
and induction of autophagy in the context of cell adaptation and survival. Therefore, new …
Comprehensive elucidation of small molecule therapeutic behavior using multitarget theory
W Mangione - 2022 - search.proquest.com
The ability to accurately determine therapeutic and adverse effects of drugs using
computational means would significantly reduce the failure rate of novel therapeutics in the …
computational means would significantly reduce the failure rate of novel therapeutics in the …
Potentially useful drugs in the treatment of COVID-19 in Primary Care
L García-Matarín, S Velilla-Zancada, E Trillo-Calvo… - Semergen, 2021 - europepmc.org
Las consecuencias de la pandemia por el SARS-CoV-2 han desbordado cualquier
previsión realizada. Hoy sabemos que el nivel de gravedad de la infección en sus fases …
previsión realizada. Hoy sabemos que el nivel de gravedad de la infección en sus fases …
Antiviral treatment
E Nagy, G Nagy, V Szijarto, R Konrat - US Patent 11,433,080, 2022 - Google Patents
A method of treating a subject in need of anti-coronavirus treatment by providing a
prophylactic or therapeutic treatment which includes an antiviral effective amount of an …
prophylactic or therapeutic treatment which includes an antiviral effective amount of an …
Az akadémiai-ipari együttműködések szerepe a gyógyszerfejlesztésben pandémia idején
GM Keserű - Scientia et Securitas, 2021 - akjournals.com
Until the turn of the millennium, pharmaceutical research and development worldwide had
traditionally taken place in pharmaceutical companies. In recent decades, however …
traditionally taken place in pharmaceutical companies. In recent decades, however …
Azelastine as antiviral treatment
E Nagy, G Nagy, V Szijarto, R Konrat - 2023 - Google Patents
OMRXBNSVRJWWAZ-UHFFFAOYSA-N n-[[4-(4-methylpiperazin-1-yl) phenyl] methyl]-1, 2-
oxazole-5-carboxamide Chemical compound C1CN (C) CCN1C (C= C1)= CC= C1CNC …
oxazole-5-carboxamide Chemical compound C1CN (C) CCN1C (C= C1)= CC= C1CNC …