Head and neck squamous cell carcinoma: update on epidemiology, diagnosis, and treatment

S Marur, AA Forastiere - Mayo Clinic Proceedings, 2016 - Elsevier
Squamous cell carcinoma arises from multiple anatomic subsites in the head and neck
region. The risk factors for development of cancers of the oral cavity, oropharynx …

Treatment of late sequelae after radiotherapy for head and neck cancer

P Strojan, KA Hutcheson, A Eisbruch, JJ Beitler… - Cancer treatment …, 2017 - Elsevier
Radiotherapy (RT) is used to treat approximately 80% of patients with cancer of the head
and neck. Despite enormous advances in RT planning and delivery, a significant number of …

Phase II randomized trial of transoral surgery and low-dose intensity modulated radiation therapy in resectable p16+ locally advanced oropharynx cancer: an ECOG …

RL Ferris, Y Flamand, GS Weinstein, S Li… - Journal of clinical …, 2022 - ascopubs.org
PURPOSE Definitive or postoperative chemoradiation (CRT) is curative for human
papillomavirus–associated (HPV+) oropharynx cancer (OPC) but induces significant toxicity …

Diagnosis, removal, or mechanical damaging of tumor using plasmonic nanobubbles

DO Lapotko, K Hleb - US Patent 10,471,159, 2019 - Google Patents
Processes of intraoperative diagnosis and elimination of tumors or micro-tumors or cancer
cells or tumor micro environment (TME) with plasmonic nanobubbles (PNBS) are disclosed …

E1308: phase II trial of induction chemotherapy followed by reduced-dose radiation and weekly cetuximab in patients with HPV-associated resectable squamous cell …

S Marur, S Li, AJ Cmelak, ML Gillison… - Journal of Clinical …, 2017 - ascopubs.org
Purpose Human papillomavirus (HPV)–associated oropharyngeal squamous cell carcinoma
(OPSCC) is treatment-responsive. Definitive chemoradiation results in high cure rates but …

Reduced-dose radiotherapy for human papillomavirus-associated squamous-cell carcinoma of the oropharynx: a single-arm, phase 2 study

AM Chen, C Felix, PC Wang, S Hsu, V Basehart… - The Lancet …, 2017 - thelancet.com
Background Head and neck cancers positive for human papillomavirus (HPV) are
exquisitely radiosensitive. We investigated whether chemoradiotherapy with reduced-dose …

Oropharyngeal carcinoma with a special focus on HPV-related squamous cell carcinoma

RL Ferris, W Westra - Annual Review of Pathology: Mechanisms …, 2023 - annualreviews.org
Human papillomavirus–positive oropharyngeal squamous cell carcinoma (HPV-OPSCC)
has one of the most rapidly increasing incidences of any cancer in high-income countries …

[HTML][HTML] Selection of patients for radiotherapy with protons aiming at reduction of side effects: the model-based approach

JA Langendijk, P Lambin, D De Ruysscher… - Radiotherapy and …, 2013 - Elsevier
Most new radiation techniques, have been introduced primarily to reduce the dose to normal
tissues in order to prevent radiation-induced side effects. Radiotherapy with protons is such …

Dysphagia-optimised intensity-modulated radiotherapy versus standard intensity-modulated radiotherapy in patients with head and neck cancer (DARS): a phase 3 …

C Nutting, L Finneran, J Roe, MA Sydenham… - The Lancet …, 2023 - thelancet.com
Background Most newly diagnosed oropharyngeal and hypopharyngeal cancers are treated
with chemoradiotherapy with curative intent but at the consequence of adverse effects on …

Low-level laser therapy/photobiomodulation in the management of side effects of chemoradiation therapy in head and neck cancer: part 2: proposed applications and …

JAEM Zecha, JE Raber-Durlacher, RG Nair… - Supportive Care in …, 2016 - Springer
Purpose There is a large body of evidence supporting the efficacy of low-level laser therapy
(LLLT), more recently termed photobiomodulation (PBM) for the management of oral …